MRC LMCB,
Laboratory for Molecular Cell Biology
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A functional green fluorescent protein-erythropoietin receptor despite physical separation of JAK2 binding site and tyrosine residues.
The Journal of biological chemistry Jul, 2002 | Pubmed ID: 11997394
The cytokine-inducible Scr homology domain-containing protein negatively regulates signaling by promoting apoptosis in erythroid progenitor cells.
The Journal of biological chemistry Jan, 2003 | Pubmed ID: 12441334
Effects of telomerase modulation in human hematopoietic progenitor cells.
Stem cells (Dayton, Ohio) , 2004 | Pubmed ID: 15342938
A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.
Genome biology , 2008 | Pubmed ID: 18387192
Quantitation of autophagy by luciferase release assay.
Autophagy Aug, 2008 | Pubmed ID: 18641457
Packing density of the erythropoietin receptor transmembrane domain correlates with amplification of biological responses.
Biochemistry Nov, 2008 | Pubmed ID: 18855427
The Feynman trajectories: determining the path of a protein using fixed-endpoint assays.
Journal of biomolecular screening Mar, 2010 | Pubmed ID: 20130209
Host-encoded reporters for the detection and purification of multiple enveloped viruses.
Journal of virological methods Aug, 2010 | Pubmed ID: 20399809
High-throughput transfection of differentiated primary neurons from rat forebrain.
Journal of biomolecular screening Jun, 2012 | Pubmed ID: 22403411
Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.
The Journal of experimental medicine Jun, 2012 | Pubmed ID: 22641382
Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor.
Cancer cell Apr, 2018 | Pubmed ID: 29634949
A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA.
Scientific reports 06, 2018 | Pubmed ID: 29899557
Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells.
Frontiers in cell and developmental biology , 2018 | Pubmed ID: 30443548
HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.
Cell reports 12, 2018 | Pubmed ID: 30517863
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.
Autophagy 06, 2019 | Pubmed ID: 30661429
Towards a data-integrated cell.
Nature communications Feb, 2019 | Pubmed ID: 30778056
Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry.
Viruses Feb, 2019 | Pubmed ID: 30791609
Using stem cell-derived neurons in drug screening for neurological diseases.
Neurobiology of aging 06, 2019 | Pubmed ID: 30925301
Author Correction: Towards a data-integrated cell.
Nature communications May, 2019 | Pubmed ID: 31113941
Seeding Induced Pluripotent Stem Cell-Derived Neurons onto 384-Well Plates.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31124113
High-Content Autophagy Analysis in iPSC-Derived Neurons Using Immunofluorescence.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31124114
High-Content Analysis of Mitochondrial Function in iPSC-Derived Neurons.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31124115
Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.
Oncogene Jul, 2019 | Pubmed ID: 31296956
Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins.
The Journal of biological chemistry Aug, 2019 | Pubmed ID: 31315929
A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan.
EMBO reports Nov, 2019 | Pubmed ID: 31566294
Agephagy - Adapting Autophagy for Health During Aging.
Frontiers in cell and developmental biology , 2019 | Pubmed ID: 31850344
On ATG4B as Drug Target for Treatment of Solid Tumours-The Knowns and the Unknowns.
Cells Dec, 2019 | Pubmed ID: 31878323
Correction: Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.
Oncogene Apr, 2020 | Pubmed ID: 32094403
Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2020 | Pubmed ID: 32329133
Modulation of endothelial organelle size as an antithrombotic strategy.
Journal of thrombosis and haemostasis : JTH Dec, 2020 | Pubmed ID: 32881285
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy Feb, 2021 | Pubmed ID: 33634751
Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia.
The European respiratory journal Oct, 2021 | Pubmed ID: 33795320
ATG4: More Than a Protease?
Trends in cell biology Jul, 2021 | Pubmed ID: 33972154
Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter.
Cell reports Jun, 2021 | Pubmed ID: 34161774
Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches.
The Biochemical journal Dec, 2021 | Pubmed ID: 34704599
Transcriptional co-activators YAP1-TAZ of Hippo signalling in doxorubicin-induced cardiomyopathy.
ESC heart failure Feb, 2022 | Pubmed ID: 34931757
Targeting Deubiquitinating Enzymes (DUBs) That Regulate Mitophagy via Direct or Indirect Interaction with Parkin.
International journal of molecular sciences Oct, 2022 | Pubmed ID: 36292958
Automated high-content imaging in iPSC-derived neuronal progenitors.
SLAS discovery : advancing life sciences R & D Mar, 2023 | Pubmed ID: 36610640