Xiang Xue

Department of Molecular & Integrative Physiology

University of Michigan

Dr. Xue’s lab is focused on studying molecular mechanisms for inflammatory bowel disease (IBD) and colorectal cancer (CRC). He utilizes cell line and enteroid cultures, mouse models, patient tissues and a wide array of molecular and biochemical methodologies. Several ongoing projects in the lab include:

Why are micronutrients essential for cancer cell growth?

How does mitochondrial metabolism regulate the progress of cancer?

Whether stress activated pathways play a role in cancer cell metabolism?

What role does hypoxia signaling have in intestinal inflammation and colorectal cancer?

What is the critical link between nutrient homeostasis, inflammation and cancer?

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