Claire Rodriguez-Lafrasse

Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing.

Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.

Subcellular compartmentalization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria?

Prevalence of drug-induced electrocardiographic pattern of the Brugada syndrome in a healthy population.

Plasma BNP and NT-proBNP assays by automated immunoanalyzers: analytical and clinical study.

Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition.

Spatiotemporal electrocardiographic characterization of ventricular depolarization and repolarization abnormalities in long QT syndrome.

Radioresistance of human carcinoma cells is correlated to a defect in raft membrane clustering.

Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells.

Differential regulation of cell death in head and neck cell carcinoma through alteration of cholesterol levels in lipid rafts microdomains.

Radiobiologic parameters and local effect model predictions for head-and-neck squamous cell carcinomas exposed to high linear energy transfer ions.

A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope.

Rapid, sensitive and inexpensive detection of SCN5A genetic variations by high resolution melting analysis.

Diversity and complexity of ceramide generation after exposure of jurkat leukemia cells to irradiation.

Biophysical characterization of a new SCN5A mutation S1333Y in a SIDS infant linked to long QT syndrome.

Contribution of long-QT syndrome genetic variants in sudden infant death syndrome.

Different mechanisms of cell death in radiosensitive and radioresistant p53 mutated head and neck squamous cell carcinoma cell lines exposed to carbon ions and x-rays.

Heat shock protein 27 as a new therapeutic target for radiation sensitization of head and neck squamous cell carcinoma.

Quantitative loss of heterozygosity analysis for urothelial carcinoma detection and prognosis.

Prevalence and spectrum of mutations in a cohort of 192 unrelated patients with hypertrophic cardiomyopathy.

[Microsatellite markers and methylation of promoters of tumour suppressor genes in bladder cancer].

Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells.

Urinary PCA3 score predicts prostate cancer multifocality.

[Value of PCA3 urinary test for prostate biopsy decision: the Lyon-Sud University Hospital experience].

Chronic prostatitis does not influence urinary PCA3 score.

DNA double-strand breaks induced by mammographic screening procedures in human mammary epithelial cells.

Targeting a cornerstone of radiation resistance: cancer stem cell.

Internalization pathways into cancer cells of gadolinium-based radiosensitizing nanoparticles.

Telomere profiling: toward glioblastoma personalized medicine.

Glutathione depletion and carbon ion radiation potentiate clustered DNA lesions, cell death and prevent chromosomal changes in cancer cells progeny.

[Cancer stem cells, cornerstone of radioresistance and perspectives for radiosensitization: glioblastoma as an example].

Impact of hyperthermic intraperitoneal chemotherapy on Hsp27 protein expression in serum of patients with peritoneal carcinomatosis.

Intraperitoneal cytokine level in patients with peritoneal surface malignancies. A study of the RENAPE (French Network for Rare Peritoneal Malignancies).

p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation.

Targeting Head and Neck Cancer Stem Cells to Overcome Resistance to Photon and Carbon Ion Radiation.

PCA3 and PCA3-based nomograms improve diagnostic accuracy in patients undergoing first prostate biopsy.

Microarray gene expression profiling and analysis of bladder cancer supports the sub classification of the T1 tumours in T1a and T1b stages.

Radiation-enhanced cell migration/invasion process: a review.

Combining ultrasmall gadolinium-based nanoparticles with photon irradiation overcomes radioresistance of head and neck squamous cell carcinoma.

[Radiation-induces increased tumor cell aggressiveness of tumors of the glioblastomas?].

Cellular and molecular portrait of eleven human glioblastoma cell lines under photon and carbon ion irradiation.

Multiparameter Phase I trials: a tool for model-based development of targeted agent combinations--example of EVESOR trial.

Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.

[Cancer stem cells: Radiotherapeutic features and therapeutic targets].

[Radiosensitivity and/or radioresistance of head and neck cancers: Biological angle].

Targeting head and neck tumoral stem cells: From biological aspects to therapeutic perspectives.

Gadolinium-Based Nanoparticles and Radiation Therapy for Multiple Brain Melanoma Metastases: Proof of Concept before Phase I Trial.

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC.

Nanoparticles in radiation oncology: From bench-side to bedside.

Influence of Dose Rate on the Cellular Response to Low- and High-LET Radiations.

MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma.

Carbon ion irradiation withstands cancer stem cells' migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC).

Immunotherapy in head and neck cancer: Harnessing profit on a system disruption.

EVESOR, a model-based, multiparameter, Phase I trial to optimize the benefit/toxicity ratio of everolimus and sorafenib.

Corrigendum: Influence of Dose Rate on the Cellular Response to Low- and High-LET Radiations.

Preclinical models in HNSCC: A comprehensive review.

Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect.

Non-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine.

Gadolinium-based nanoparticles as sensitizing agents to carbon ions in head and neck tumor cells.

Dual "mAb" HER family blockade in head and neck cancer human cell lines combined with photon therapy.

Evaluation of pre-analytical conditions and comparison of the performance of several digital PCR assays for the detection of major mutations in circulating DNA from non-small cell lung cancers: the CIRCAN_0 study.

Cross-platform comparison for the detection of RAS mutations in cfDNA (ddPCR Biorad detection assay, BEAMing assay, and NGS strategy).

ROS Production and Distribution: A New Paradigm to Explain the Differential Effects of X-ray and Carbon Ion Irradiation on Cancer Stem Cell Migration and Invasion.

Profiling of circulating tumor DNA in plasma of non-small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in future application in mimicking circulating tumor cells.