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UCBL1,
UMR/CNRS 5822,
Laboratoire de Radiobiologie Cellulaire Moléculaire,
UCBL1, UMR/CNRS 5822, Laboratoire de Radiobiologie Cellulaire Moléculaire
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Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing.
International journal of cancer. Journal international du cancer Oct, 2002 | Pubmed ID: 12237902
Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.
Oncogene Apr, 2004 | Pubmed ID: 15048093
Radioresistance of human carcinoma cells is correlated to a defect in raft membrane clustering.
Free radical biology & medicine Sep, 2007 | Pubmed ID: 17664132
Differential regulation of cell death in head and neck cell carcinoma through alteration of cholesterol levels in lipid rafts microdomains.
Biochemical pharmacology Feb, 2008 | Pubmed ID: 17996216
Radiobiologic parameters and local effect model predictions for head-and-neck squamous cell carcinomas exposed to high linear energy transfer ions.
International journal of radiation oncology, biology, physics Jun, 2008 | Pubmed ID: 18234427
Different mechanisms of cell death in radiosensitive and radioresistant p53 mutated head and neck squamous cell carcinoma cell lines exposed to carbon ions and x-rays.
International journal of radiation oncology, biology, physics May, 2009 | Pubmed ID: 19362238
Targeting a cornerstone of radiation resistance: cancer stem cell.
Cancer letters Sep, 2012 | Pubmed ID: 22459349
Telomere profiling: toward glioblastoma personalized medicine.
Molecular neurobiology Feb, 2013 | Pubmed ID: 23065374
[Cancer stem cells, cornerstone of radioresistance and perspectives for radiosensitization: glioblastoma as an example].
Bulletin du cancer Dec, 2012 | Pubmed ID: 23228708
p53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation.
BMC cancer , 2013 | Pubmed ID: 23530619
Targeting Head and Neck Cancer Stem Cells to Overcome Resistance to Photon and Carbon Ion Radiation.
Stem cell reviews Aug, 2013 | Pubmed ID: 23955575
Radiation-enhanced cell migration/invasion process: a review.
Critical reviews in oncology/hematology Nov, 2014 | Pubmed ID: 24908570
[Radiation-induces increased tumor cell aggressiveness of tumors of the glioblastomas?].
Bulletin du cancer Sep, 2014 | Pubmed ID: 25296414
Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma.
Molecular cancer , 2015 | Pubmed ID: 26183089
[Cancer stem cells: Radiotherapeutic features and therapeutic targets].
Bulletin du cancer Jan, 2016 | Pubmed ID: 26702506
[Radiosensitivity and/or radioresistance of head and neck cancers: Biological angle].
Bulletin du cancer Jan, 2016 | Pubmed ID: 26702507
Targeting head and neck tumoral stem cells: From biological aspects to therapeutic perspectives.
World journal of stem cells Jan, 2016 | Pubmed ID: 26839637
Influence of Dose Rate on the Cellular Response to Low- and High-LET Radiations.
Frontiers in oncology , 2016 | Pubmed ID: 27014633
Carbon ion irradiation withstands cancer stem cells' migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC).
Oncotarget Jul, 2016 | Pubmed ID: 27374096
Preclinical models in HNSCC: A comprehensive review.
Oral oncology Feb, 2017 | Pubmed ID: 28109468
Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect.
British journal of cancer May, 2017 | Pubmed ID: 28407653
Gadolinium-based nanoparticles as sensitizing agents to carbon ions in head and neck tumor cells.
Nanomedicine : nanotechnology, biology, and medicine Nov, 2017 | Pubmed ID: 28779947
Dual "mAb" HER family blockade in head and neck cancer human cell lines combined with photon therapy.
Scientific reports Sep, 2017 | Pubmed ID: 28939847
Université de Lyon
Hospices-Civils-de-Lyon, Centre Hospitalier Lyon-Sud
Université Lyon 1
Centre Hospitalier Lyon-Sud
Marion Gilormini1,
Anne-Sophie Wozny1,2,
Priscillia Battiston-Montagne1,
Dominique Ardail1,2,
Gersende Alphonse1,2,
Claire Rodriguez-Lafrasse1,2
1UCBL1, UMR/CNRS 5822, Laboratoire de Radiobiologie Cellulaire Moléculaire, Université de Lyon,
2, Hospices-Civils-de-Lyon, Centre Hospitalier Lyon-Sud
Jean-Baptiste Guy*,1,2,
Sophie Espenel*,1,2,
Alexis Vallard1,2,
Anne-Sophie Wozny1,3,
Dominique Ardail1,3,
Gersende Alphonse1,3,
Chloé Rancoule1,2,
Claire Rodriguez-Lafrasse1,3,
Nicolas Magne1,2
1UMR CNRS 5822 /IN2P3, IPNL, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Université Lyon 1,
2Département de Radiothérapie, Institut de Cancérologie de la Loire - Lucien Neuwirth,
3Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud
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