A Randomized, Sham-Controlled Trial of Cranial Electrical Stimulation for Fibromyalgia Pain and Physical Function, Using Brain Imaging BiomarkersAnna Ree 1, Benjamin Rapsas 2, Chanse Denmon 1, Mark Vernon 1, Sheila AM Rauch 1,2, Ying Guo 3, Xiangqin Cui 1,3, Jennifer S Stevens 1,2, Venkatagiri Krishnamurthy 1,2, Vitaly Napadow 4, Jessica A Turner 5, Anna Woodbury 1,2
1Atlanta Veterans Affairs Healthcare System, 2Emory University School of Medicine, 3Rollins School of Public Health, 4Spaulding Rehabilitation Hospital, Harvard Medical School, 5The Ohio State University Wexner Medical Center
The current study is a randomized, placebo-controlled trial to determine the efficacy of cranial electrical stimulation (CES) for improving pain and function in fibromyalgia and further develop resting functional connectivity magnetic resonance imaging (rs-fcMRI) as a clinical tool to assess the neural correlates and mechanisms of chronic pain and analgesic response.
