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German Center for Neurodegenerative Diseases (DZNE) eV.

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Biology

Cost-Efficient Transcriptomic-Based Drug Screening
Jacqueline Leidner 1,2, Heidi Theis 3, Michael Kraut 3, Alice Ragogna 1, Marc Beyer 1,3,4, Joachim Schultze 1,2,3, Jonas Schulte-Schrepping 1,2, Caterina Carraro 1,2, Lorenzo Bonaguro 1,2
1Systems Medicine, German Center for Neurodegenerative Diseases (DZNE) eV., 2Genomics & Immunoregulation, LIMES Institute, University of Bonn, 3PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn, 4Immunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE) eV.

This protocol describes a workflow from ex vivo or in vitro cell cultures to transcriptomic data pre-processing for cost-effective transcriptome-based drug screening.

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