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State University of New York Geneseo College

1 ARTICLES PUBLISHED IN JoVE

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Biochemistry

Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
Kazushige Yokoyama 1, Christopher Kolilias 1, Victoria Brzezinski 1, Akane Ichiki 1
1Department of Chemistry and Biochemistry, State University of New York Geneseo College

Here, we present a systematic method describing the quasi-reversible self-assembly of the amyloid beta 1-40 (Aβ1-40)-coated 20 nm gold aggregates. The nano-size-dependent quasi-reversible networking between peptides was correlated with specific amino acids or sections of the Aβ1-40 monomer.

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