Caliper- a PerkinElmer Company
2 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
4D Multimodality Imaging of Citrobacter rodentium Infections in Mice
James William Collins 1, Jeffrey A Meganck 2, Chaincy Kuo 2, Kevin P Francis 2, Gad Frankel 1
1MRC Centre for Molecular Bacteriology and Infection, Division of Cell & Molecular Biology, Imperial College London, 2Preclinical Imaging, Caliper- A PerkinElmer Company
Multi-modality imaging is a valuable approach for studying bacterial colonization in small animal models. This protocol outlines infection of mice with bioluminescent Citrobacter rodentium and the longitudinal monitoring of bacterial colonization using composite 3D diffuse light imaging tomography with μCT imaging to create a 4D movie of C. rodentium infection.
Medicine
Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
Xueli Zhang 1,2, Chaincy Kuo 3, Anna Moore 1, Chongzhao Ran 1
1Molecular Imaging Laboratory, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital/Harvard Medical School, 2Center for Drug Discovery, School of Pharmacy, China Pharmaceutical University, 3Perkin Elmer
In this video report, we show the application of Cerenkov Luminescence Imaging (CLI) for interscapular brown adipose tissue in mice under activated and depressed conditions.
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