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Qingdao University

6 ARTICLES PUBLISHED IN JoVE

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JoVE Core

Fabrication and Operation of a Nano-Optical Conveyor Belt
Jason Ryan 1, Yuxin Zheng 1, Paul Hansen 1, Lambertus Hesselink 2
1Electrical Engineering, Stanford University, 2Applied Physics, Stanford University

The scalability and resolution of conventional optical manipulation techniques are limited by diffraction. We circumvent the diffraction limit and describe a method of optically transporting nanoparticles across a chip using a gold surface patterned with a path of closely spaced C-shaped plasmonic resonators.

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Medicine

The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation
Junjie Liang *1,2, Yuanyuan Guo *1,2, Yuxin Zheng 1,2, Shijuan Lang 1, Hongxin Chen 1,2, Yaoyao You 1,2, Bryan O’Young 3,4, Haining Ou *1,2, Qiang Lin *1,2
1Department of Rehabilitation, The Fifth Affiliated Hospital of Guangzhou Medical University, 2Experiment Education Model Center of Rehabilitation Medicine, Guangzhou Medical University, 3Department of Physical Medicine and Rehabilitation, Geisinger Health System, 4Department of Rehabilitation Medicine, New York University School of Medicine

Here, based on a clinician’s point-of-view, we propose a two-model lower body positive pressure (LBPP) protocol (walking and squatting models) in addition to a clinical, functional assessment methodology, including details for further encouragement of the development of non-drug surgical intervention strategies in knee osteoarthritis patients. However, we only present the effect of LBPP training in improvement of pain and knee function in one patient through three-dimensional gait analysis. The exact, long-term effects of this approach should be explored in future studies.

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Developmental Biology

Using Chicken Embryo as a Powerful Tool in Assessment of Developmental Cardiotoxicities
Qixiao Jiang 1, Xiaohui Xu 1, Jamie C. DeWitt 2, Yuxin Zheng 1
1School of Public Health, Qingdao University, 2Department of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University

Chicken embryos, as a classical developmental model, are used in our lab to assess developmental cardiotoxicities following exposure to various environmental contaminants. Exposure methods and morphological/functional assessment methods established are described in this manuscript.

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Environment

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
He Sun *1, Wenting Cheng *1, Xinyi Zhang 1, Zhaolong Sun 1, Haowei Sun 1, Shuhan Tian 1, Jinglong Tang 1
1Department of Environmental and Occupational Health, School of Public Health, Qingdao University

This article describes a detailed experimental protocol for measuring the carbon content of airway macrophages with the aim of assessing the internal exposure dose at the level of individual particulate matter exposure.

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Environment

Studying the Effects of Inhaled Environmental Pollutants on Olfactory Function in Mice
Linfei Chen 1, Haowen Chen 1, Yanting Li 1, Jiaqi Kong 1, Xiaoya Ji 1, Jinglong Tang 1
1Department of Environmental and Occupational Health, School of Public Health, Qingdao University

This paper provides a detailed description of the buried food test and social odor discrimination experiment to assess the effects of inhaled environmental pollutants exposure on olfactory function in mice.

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Environment

A High-Throughput Screening Approach for Evaluating the Binding Affinity of Environmental Pollutants to Nuclear Receptors
Lanchao Sun 1, Chuanhai Li 1
1School of Public Health, Qingdao University

This protocol describes a high-throughput screening system that uses fluorescence polarization of a specific fluorescent probe binding to a nuclear receptor as a readout for screening environmental pollutants.

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