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Biogen Idec

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Neuroscience

Derivation of Glial Restricted Precursors from E13 mice
André W. Phillips 1,2, Sina Falahati 1,2, Roshi DeSilva 1,3, Irina Shats 2, Joel Marx 1, Edwin Arauz 1, Douglas A. Kerr 4, Jeffrey D. Rothstein 2,5, Michael V. Johnston 1,2,6, Ali Fatemi 1,2,6
1Hugo W. Moser Research Institute at Kennedy Krieger, Johns Hopkins University, 2Department of Neurology, Johns Hopkins School of Medicine, 3University of Maryland , 4Experimental Neurology, Biogen Idec, 5The Brain Science Institute, Johns Hopkins School of Medicine, 6Department of Pediatrics, Johns Hopkins School of Medicine

This protocol outlines the derivation of Glial Restricted Precursors from fetal spinal cords and maintained in vitro either for transplantation or for the study of oligodendrocytic lineage.

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