S'identifier

The basal lamina is a thin extracellular layer that lies underneath the cells and separates them from other tissues. The three layers of the basal lamina are lamina lucida, lamina densa and lamina reticularis. The basal lamina, a mixture of glycoproteins and collagen, provides an attachment site for the epithelium, separating it from underlying connective tissue. The framework of basal lamina has other essential proteins such as laminins mesh, perlecan, entactin, and type IV collagen.

Proteins like integrins and dystroglycan in the cell membranes attach to proteins like laminins and fibronectin in the basal lamina, associating the cell with the extracellular matrix of the connective tissue. The basal lamina present in the kidney, serves as a molecular filter, whereas, at the neuromuscular junction, it surrounds the muscle cells, separating them from the nerve cells at the synapse. The basal lamina further helps regenerate the synapse after an injury and aids in localizing acetylcholine receptors.

Tags

Basal LaminaExtracellular MatrixECMLamina LucidaLamina DensaLamina ReticularisGlycoproteinsCollagenLamininsPerlecanEntactinType IV CollagenIntegrinsDystroglycanMolecular FilterNeuromuscular JunctionSynapseAcetylcholine Receptors

Du chapitre 27:

article

Now Playing

27.9 : Basal Lamina are the Specialized Form of ECM

Extracellular Matrix in Animals

2.6K Vues

article

27.1 : La matrice extracellulaire

Extracellular Matrix in Animals

8.7K Vues

article

27.2 : Les glycosaminoglycanes

Extracellular Matrix in Animals

4.6K Vues

article

27.3 : Les collagènes sont les principales protéines structurelles de la MEC

Extracellular Matrix in Animals

3.9K Vues

article

27.4 : Collagène associé aux fibrilles

Extracellular Matrix in Animals

2.4K Vues

article

27.5 : L’élastine est responsable de l’élasticité des tissus

Extracellular Matrix in Animals

2.2K Vues

article

27.6 : Les fibronectines connectent les cellules avec l’ECM

Extracellular Matrix in Animals

2.3K Vues

article

27.7 : Protéoglycanes matriciels et glycoprotéines

Extracellular Matrix in Animals

3.7K Vues

article

27.8 : Rôle des métalloprotéases matricielles dans la dégradation de l’ECM

Extracellular Matrix in Animals

2.3K Vues

article

27.10 : Les laminines sont les protéines adhésives de la lame basale

Extracellular Matrix in Animals

2.1K Vues

article

27.11 : Collagène de type IV de la lame basale

Extracellular Matrix in Animals

2.1K Vues

JoVE Logo

Confidentialité

Conditions d'utilisation

Politiques

Recherche

Enseignement

À PROPOS DE JoVE

Copyright © 2025 MyJoVE Corporation. Tous droits réservés.