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Bryant University

2 ARTICLES PUBLISHED IN JoVE

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Biochemistry

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
Mika Gallati 1, Bryant Point 1, Christopher W. Reid 1,2
1Department of Science and Technology, Bryant University, 2Center for Health and Behavioral Sciences, Bryant University

A detailed protocol is presented for preparing the bacteriostatic diamide masarimycin, a small molecule probe that inhibits the growth of Bacillus subtilis and Streptococcus pneumoniae by targeting cell wall degradation. Its application as a chemical probe is demonstrated in synergy/antagonism assays and morphological studies with B. subtilis and S. pneumoniae.

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Genetics

Getting an A with the 3Cs: Chromosome Conformation Capture for Undergraduates
Acadia Joniec *1, Joseph Leszczynski *1, Sokhna Ndoye *1, Jillian Sylvia *1, Steven E. Weicksel 1,2
1Department of Biological and Biomedical Sciences, Bryant University, 2Center of Health and Behavioral Sciences, Bryant University

Here, we present an adaption of the chromosome conformation capture (3C) technique in detail with an emphasis on undergraduate involvement and learning.

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