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Le Moyne College

1 ARTICLES PUBLISHED IN JoVE

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Behavior

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
Candace N. Receno 1, Caitlin M. Cunningham 2, Brianna E. Eassa 1, Rebecca Purdy 1, Lara R. DeRuisseau 1
1Department of Biological Sciences, Le Moyne College, 2Department of Mathematics, Statistics and Computer Science, Le Moyne College

Unrestrained barometric plethysmography is used to quantify the pattern of breathing in awake mice. We show that 15 s segments under a standardized protocol display similar values to an extended duration of quiet breathing. This methodology also allows for the quantification of apnea and augmented breaths during the first hour in the chamber.

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