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The Methodist Hospital Research Institute, Houston

1 ARTICLES PUBLISHED IN JoVE

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Biology

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Xukui Wang 1, Laurie J. Minze 2, Zheng-Zheng Shi 1
1Department of Translational Imaging, The Methodist Hospital Research Institute, Houston, 2Diabetes Research Center, The Methodist Hospital Research Institute, Houston

A method of functional imaging of mouse brown adipose tissue (BAT) is described in which cold-stimulated uptake of 18F-Fluorodeoxyglucose (FDG) in BAT is non-invasively assessed with a standardized micro-PET/CT protocol. This method is robust and sensitive to detect differences in BAT activities in mouse models.

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