St. Anne's University Hospital

2 ARTICLES PUBLISHED IN JoVE

Bioengineering

Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention

Susheil Uthamaraj¹, Brandon J. Tefft², Ota Hlinomaz³, Gurpreet S. Sandhu², Dan Dragomir-Daescu^1,4

¹Division of Engineering, Mayo Clinic, ²Division of Cardiovascular Diseases, Mayo Clinic, ³Department of Cardioangiology, ICRC, St. Anne's University Hospital, ⁴Mayo Clinic College of Medicine

Our goals were to design, manufacture and test ferromagnetic stents for endothelial cell capture. Ten stents were tested for fracture and 10 more stents were tested for retained magnetism. Finally, 10 stents were tested in-vitro and 8 more stents were implanted in 4 pigs to show cell capture and retention.

Medicine

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

Susheil Uthamaraj¹, Brandon J. Tefft², Soumen Jana², Ota Hlinomaz³, Manju Kalra⁴, Amir Lerman², Dan Dragomir-Daescu^1,5, Gurpreet S. Sandhu²

¹Division of Engineering, Mayo Clinic, ²Department of Cardiovascular Diseases, Mayo Clinic, ³Department of Cardioangiology, ICRC, St. Anne's University Hospital, ⁴Department of Vascular Surgery, Mayo Clinic, ⁵Department of Physiology and Biomedical Engineering, Mayo Clinic

In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.