University and hospital trust of Verona

4 ARTICLES PUBLISHED IN JoVE

Cancer Research

Laparoscopic Pancreatoduodenectomy With Modified Blumgart Pancreaticojejunostomy

Matteo De Pastena^1,2, Jony van Hilst¹, Thijs de Rooij¹, Olivier R Busch¹, Michael F Gerhards³, Sebastiaan Festen³, Marc G Besselink¹

¹Department of Surgery, Cancer Center Amsterdam, Academic Medical Center, ²General and Pancreatic Surgery Department, Pancreas Institute, University and Hospital Trust of Verona, ³Department of Surgery, OLVG

Laparoscopic pancreatoduodenctomy (LPD) may offer advantages over open pancreatoduodenectomy, including early postoperative mobilization, less delayed gastric emptying and a shorter hospital stay. However, LPD is technically challenging and not well-standardized, especially regarding the pancreatic anastomosis. We describe a standardized technique for the pancreatic anastomosis during LPD: modified Blumgart pancreaticojejunostomy.

Behavior

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Caterina Vicentini¹, Andrea Mafficini¹, Michele Simbolo², Matteo Fassan³, Pietro Delfino², Rita Teresa Lawlor¹, Borislav Rusev¹, Aldo Scarpa^1,2, Vincenzo Corbo^1,2

¹ARC-Net Research Centre, University and Hospital Trust of Verona, ²Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, ³Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, University of Padua

This article describes a method to identify clonal and subclonal alterations among different specimens from a given patient. Although the experiments described here focus on a specific tumor type, the approach is broadly applicable to other solid tumors.

Medicine

Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis

Alberto Balduzzi^*1,2, Maurice J. W. Zwart^*1, Rens M. A. Kempeneers¹, Marja A. Boermeester¹, Olivier R. Busch¹, Marc G. Besselink¹

¹Department of Surgery, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, ²General and Pancreatic Surgery Department, Pancreas Institute, University and Hospital Trust of Verona

Robotic lateral pancreaticojejunostomy (RLPJ) may be used in patients with painful, morphine dependent, chronic pancreatitis and a dilated main pancreatic duct. We describe a standardized and reproducible technique for RLPJ, which includes transection of the gastroduodenal artery.

Medicine

Laparoscopic Radical Left Pancreatectomy for Pancreatic Cancer: Surgical Strategy and Technique Video

Frederique L. Vissers¹, Maurice J.W. Zwart¹, Alberto Balduzzi^1,3, Maarten Korrel¹, Sanne Lof², Mohammad Abu Hilal^*2, Marc G. Besselink^*1

¹Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, ²Department of Surgery, Southampton University Hospital NHS Foundation Trust, ³General and Pancreatic Surgery Department, Pancreas Institute, University and Hospital Trust of Verona

Oncologically safe left pancreatectomy requires radical resection (R0), Gerota’s (perirenal) fascia resection, and adequate lymph node dissection. This study describes the technical details of laparoscopic radical left pancreatectomy (LRLP), used in the first international multicenter randomized trial comparing minimally invasive with open left pancreatectomy for pancreatic cancer, the DIPLOMA trial.