Korea Institute of Machinery and Materials

2 ARTICLES PUBLISHED IN JoVE

Engineering

Multiscale Structures Aggregated by Imprinted Nanofibers for Functional Surfaces

Yeonho Jeong^*1, Seok Kim^*2, Nicholas Xuanlai Fang², Seunghang Shin¹, Hyunmin Choi¹, Seonjun Kim¹, Sin Kwon³, Young Tae Cho¹

¹Department of Mechanical Engineering, Changwon National University, ²Department of Mechanical Engineering, Massachusetts Institute of Technology, ³Printed Electronics Research Team, Korea Institute of Machinery and Materials

Presented is an easy method to fabricate nano-micro multiscale structures, for functional surfaces, by aggregating nanofibers fabricated using an anodic aluminum oxide filter.

Bioengineering

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

In Gul Kim¹, Yanru Wu², Su A. Park³, Hana Cho¹, Jung-Woog Shin², Eun-Jae Chung¹

¹Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University, College of Medicine, ²Department of Biomedical Engineering, Inje University, Gimhae, ³Department of Nature-Inspired Nanoconvergence Systems, Korea Institute of Machinery and Materials

Esophageal reconstruction is a challenging procedure, and development of a tissue-engineered esophagus that enables regeneration of esophageal mucosa and muscle and that can be implanted as an artificial graft is necessary. Here, we present our protocol to generate an artificial esophagus, including scaffold manufacturing, bioreactor cultivation, and various surgical techniques.