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National and Kapodistrian University of Athens

1 ARTICLES PUBLISHED IN JoVE

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Biology

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Anna Hadjihambi *1,2, Rallia-Iliana Velliou *3, Panagiotis Tsialios 4, Aigli-Ioanna Legaki 3, Antonios Chatzigeorgiou *3, Maritina G. Rouchota *4
1The Roger Williams Institute of Hepatology London, Foundation for Liver Research, 2Faculty of Life Sciences and Medicine, King's College London, 3Department of Physiology, Medical School, National and Kapodistrian University of Athens, 4BIOEMTECH, Lefkippos Attica Technology Park NCSR "Demokritos"

Using a diet-induced non-alcoholic fatty liver disease (NAFLD) mouse model, we describe the use of novel in vivo micro-computed tomography imaging techniques as a non-invasive method to assess the progression stages of NAFLD, focusing predominantly on the hepatic vascular network due to its significant involvement in NAFLD-related hepatic dysregulation.

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