Database-guided Flow-cytometry for Evaluation of Bone Marrow Myeloid Cell MaturationCarmen Mariana Aanei 1, Marie-Christine Jacob 2, Richard Veyrat-Masson 3, Tiphanie Picot 1, Maria Alessandra Rosenthal-Allieri 4, Anne-Catherine Lhoumeau 5, Michel Ticchioni 4, Florent Dumezy 6, Lydia Campos Catafal 1
1Department of Hematology, University Hospital of Saint-Etienne, 2Department of Immunology, University Hospital of Grenoble-Alpes, 3Department Hematology, University Hospital of Clermont-Ferrand, 4Department of Immunology, University Hospital of Nice, 5Department of Biopathology, Institute Paoli-Calmettes, 6Department of Hematology, University Hospital of Lille
The MDS diagnosis is difficult in the absence of morphological criteria or non-informative cytogenetics. MFC could help refine the MDS diagnostic process. To become useful for clinical practice, the MFC analysis must be based on parameters with sufficient specificity and sensitivity, and data should be reproducible between different operators.
