A Hyperandrogenic Mouse Model to Study Polycystic Ovary SyndromePing Xue 1, Zhiqiang Wang 1, Xiaomin Fu 1,2, Junjiang Wang 1,3, Gopika Punchhi 1, Andrew Wolfe 1,4, Sheng Wu 1,4,5
1Department of Pediatrics, Johns Hopkins University School of Medicine, 2Department of Health, Beijing Military General Hospital, 3Southern Medical University, 4Department of Molecular and Cellular Physiology, Johns Hopkins University School of Medicine, 5Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine
We describe the development of a lean PCOS-like mouse model with dihydrotestosterone pellet to study the pathophysiology of PCOS and the offspring from these PCOS-like dams.
