Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee PainHollis E. Krug 1,2, Christopher Dorman 2, Nicole Blanshan 2, Sandra Frizelle 2, Maren Mahowald 1,2
1Department of Medicine, University of Minnesota, 2Research Department, VA Health Care Center
We have developed an evoked measure of arthritis pain and coupled it with a standardized method for measuring spontaneous pain in different murine models of chemically induced arthritis. These measures are sensitive and reproducible for different types of joint pain.
