Intraventricular Transplantation of Engineered Neuronal Precursors for In Vivo Neuroarchitecture StudiesSimone Chiola 1, Manuela Santo 1, Antonello Mallamaci 1
1Laboratory of Cerebral Cortex Development, SISSA
Based on in vitro lentiviral engineering of neuronal precursors, their co-transplantation into wild-type brains and paired morphometric evaluation of "test" and "control" derivatives, this method allows accurate modeling of in vivo gene control of neocortical neuron morphology in a simple and affordable way.
