I-Shou University

3 ARTICLES PUBLISHED IN JoVE

Medicine

Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model

Che-Wei Wu^1,2,3, Tzu-Yen Huang², Hui-Chun Chen⁴, Hsiu-Ya Chen⁵, Tsung-Yi Tsai², Pi-Ying Chang⁵, Yi-Chu Lin², Hsin-Yi Tseng², Pao-Chu Hun⁶, Xiaoli Liu⁷, Hui Sun⁷, Gregory W. Randolph⁸, Gianlorenzo Dionigi⁹, Feng-Yu Chiang^2,3, I-Cheng Lu^5,10,11

This study aims to develop a standard protocol of intra-operative neural monitoring of thyroid surgery in a porcine model. Here, we present a protocol to demonstrate general anesthesia, to compare different types of electrodes, and to investigate the electrophysiological characteristics of the normal and injured recurrent laryngeal nerves.

Medicine

Investigation of the Electrophysiological and Thermographic Safety Parameters of Surgical Energy Devices During Thyroid and Parathyroid Surgery in a Porcine Model

Hsin-Yi Tseng¹, Tzu-Yen Huang¹, Jia Joanna Wang^1,2, Yi-Chu Lin¹, I-Cheng Lu³, Feng-Yu Chiang⁴, Gianlorenzo Dionigi^5,6, Gregory W. Randolph⁷, Che-Wei Wu^1,8

¹Department of Otorhinolaryngology-Head and Neck Surgery, International Thyroid Surgery Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, ²Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, ³Department of Anesthesiology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, ⁴Department of Otolaryngology-Head and Neck Surgery, E-Da Hospital, I-Shou University, ⁵Division of General Surgery, Endocrine Surgery Section, Istituto Auxologico Italiano (IRCCS), ⁶Department of Pathophysiology and Transplantation, Faculty of Medicine and Surgery, University of Milan, ⁷Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, ⁸Center for Liquid Biopsy and Cohort Research, and Faculty of Medicine, College of Medicine, Kaohsiung Medical University

The safe application of newly developed surgical energy devices in thyroid/parathyroid surgery attracts the attention of surgeons. Animal experimental models can avoid unnecessary trials and errors in human surgery. This report aims to demonstrate electrophysiological and thermographic methods to evaluate the safety parameters of SEDs in thyroid/parathyroid surgery.

Medicine

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage

Min-Yu Chang^*1,2, Hsi-Hao Wang^*1,2, Li-Hung Chen^*1, Jhen Gao^*1, Shih-Yuan Hung^1,2, Yuan-Yow Chiou^3,4, Yi-Che Lee^1,2,5

¹School of Medicine, College of Medicine, I-Shou University, ²Division of Nephrology, Department of Internal Medicine, E-DA Hospital, ³Department of Pediatrics, National Cheng Kung University Hospital, ⁴Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, ⁵Division of Nephrology, Department of Internal Medicine, E-DA Dachang Hospital

The present protocol establishes a peritoneal dialysis (PD) mouse model of chlorhexidine gluconate (CG)-induced peritoneal fibrosis. The current model is simple and easy to use compared to other PD animal models.