Department of Chemistry,
Worm Institute of Research and Medicine (WIRM)
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Aqueous aldol catalysis by a nicotine metabolite.
Journal of the American Chemical Society Apr, 2002 | Pubmed ID: 11916401
Soluble polymers as scaffolds for recoverable catalysts and reagents.
Chemical reviews Oct, 2002 | Pubmed ID: 12371887
A previously undescribed chemical link between smoking and metabolic disease.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2002 | Pubmed ID: 12403823
High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins.
The Journal of organic chemistry May, 2003 | Pubmed ID: 12713377
Glycation of the amyloid beta-protein by a nicotine metabolite: a fortuitous chemical dynamic between smoking and Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2003 | Pubmed ID: 12815102
Catalysis of the photo-Fries reaction: antibody-mediated stabilization of high energy states.
Journal of the American Chemical Society Dec, 2003 | Pubmed ID: 14664584
Antibody-catalyzed oxidative degradation of nicotine using riboflavin.
Bioorganic & medicinal chemistry Sep, 2004 | Pubmed ID: 15336277
Immunological consequences of methamphetamine protein glycation.
Journal of the American Chemical Society Sep, 2004 | Pubmed ID: 15366884
Nornicotine aqueous aldol reactions: synthetic and theoretical investigations into the origins of catalysis.
The Journal of organic chemistry Oct, 2004 | Pubmed ID: 15387581
A precipitator for the detection of thiophilic metals in aqua.
Journal of the American Chemical Society Dec, 2004 | Pubmed ID: 15600364
Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2005 | Pubmed ID: 15623555
Enantioreversal in the sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer.
The Journal of organic chemistry Mar, 2005 | Pubmed ID: 15730294
Hammett correlation of nornicotine analogues in the aqueous aldol reaction: implications for green organocatalysis.
The Journal of organic chemistry Apr, 2005 | Pubmed ID: 15845010
Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy.
Expert opinion on biological therapy Jun, 2005 | Pubmed ID: 15952908
Toward cocaine esterase therapeutics.
Journal of the American Chemical Society Jul, 2005 | Pubmed ID: 16011362
Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 16014706
Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A.
FEBS letters Oct, 2005 | Pubmed ID: 16198354
Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library.
Biochemistry Nov, 2005 | Pubmed ID: 16274232
A site-specific bifunctional protein labeling system for affinity and fluorescent analysis.
Bioconjugate chemistry Nov-Dec, 2005 | Pubmed ID: 16287229
Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones.
Journal of molecular biology Jan, 2006 | Pubmed ID: 16307757
Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy.
The AAPS journal , 2005 | Pubmed ID: 16353936
Complete reaction cycle of a cocaine catalytic antibody at atomic resolution.
Structure (London, England : 1993) Feb, 2006 | Pubmed ID: 16472740
Emerging chemical and biological approaches for the preparation of discovery libraries.
Drug discovery today Feb, 2006 | Pubmed ID: 16533712
Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: a new wrinkle in botulinum neurotoxin.
Journal of the American Chemical Society Apr, 2006 | Pubmed ID: 16568962
Enamine-based aldol organocatalysis in water: are they really "all wet"?
Angewandte Chemie (International ed. in English) Dec, 2006 | Pubmed ID: 17001595
Unexpected acetylcholinesterase activity of cocaine esterases.
Journal of the American Chemical Society Dec, 2006 | Pubmed ID: 17131989
A molecular link between the active component of marijuana and Alzheimer's disease pathology.
Molecular pharmaceutics Nov-Dec, 2006 | Pubmed ID: 17140265
The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication.
ACS chemical biology Jul, 2006 | Pubmed ID: 17163773
An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2007 | Pubmed ID: 17293454
Technological advancements for the detection of and protection against biological and chemical warfare agents.
Chemical Society reviews Mar, 2007 | Pubmed ID: 17325785
Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol.
Journal of the American Chemical Society Mar, 2007 | Pubmed ID: 17335216
Positional linker effects in haptens for cocaine immunopharmacotherapy.
Bioorganic & medicinal chemistry letters Aug, 2007 | Pubmed ID: 17531484
Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17592122
Phage escape libraries for checkmate analysis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17646645
NMR detection of adventitious xylose binding to the quorum-sensing protein SdiA of Escherichia coli.
Bioorganic & medicinal chemistry letters Nov, 2007 | Pubmed ID: 17889538
Synthesis and structure-activity relationships of second-generation hydroxamate botulinum neurotoxin A protease inhibitors.
Bioorganic & medicinal chemistry letters Dec, 2007 | Pubmed ID: 17951059
Investigating novel therapeutic targets and molecular mechanisms to treat botulinum neurotoxin A intoxication.
Future microbiology Dec, 2007 | Pubmed ID: 18041908
Biologically templated organic polymers with nanoscale order.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18216240
Nornicotine-organocatalyzed aqueous reduction of alpha,beta-unsaturated aldehydes.
Chemical communications (Cambridge, England) Dec, 2007 | Pubmed ID: 18361380
Interspecies and interkingdom communication mediated by bacterial quorum sensing.
Chemical Society reviews Jul, 2008 | Pubmed ID: 18568160
Major sperm protein as a diagnostic antigen for onchocerciasis.
Bioorganic & medicinal chemistry Aug, 2008 | Pubmed ID: 18632276
The strange case of the botulinum neurotoxin: using chemistry and biology to modulate the most deadly poison.
Angewandte Chemie (International ed. in English) , 2008 | Pubmed ID: 18844202
Prevention of drug-induced memory impairment by immunopharmacotherapy.
Journal of medicinal chemistry Nov, 2008 | Pubmed ID: 18921991
Function-oriented synthesis applied to the anti-botulinum natural product toosendanin.
Bioorganic & medicinal chemistry Feb, 2009 | Pubmed ID: 19131252
Predicting protein evolution in vitro by phage escape technology.
Molecular bioSystems Feb, 2009 | Pubmed ID: 19156257
Bimodal modulation of the botulinum neurotoxin protein-conducting channel.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2009 | Pubmed ID: 19164566
Drugs of abuse that mediate advanced glycation end product formation: a chemical link to disease pathology.
Accounts of chemical research May, 2009 | Pubmed ID: 19275211
Monoclonal antibodies with orthogonal azaspiracid epitopes.
Chembiochem : a European journal of chemical biology Jul, 2009 | Pubmed ID: 19492388
A critical evaluation of a nicotine vaccine within a self-administration behavioral model.
Molecular pharmaceutics Apr, 2010 | Pubmed ID: 20104903
A bacteriophage-based platform for rapid trace detection of proteases.
Journal of the American Chemical Society Sep, 2010 | Pubmed ID: 20812737
Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis.
PLoS neglected tropical diseases , 2010 | Pubmed ID: 20957145
Characterization of differences between blood sample matrices in untargeted metabolomics.
Analytical chemistry Feb, 2011 | Pubmed ID: 21175165
Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design.
ACS chemical neuroscience Jun, 2011 | Pubmed ID: 21743830
Sensing the deadliest toxin: technologies for botulinum neurotoxin detection.
Toxins Jan, 2010 | Pubmed ID: 22069545
A coincidence detector triggers botulinum neurotoxin translocation.
Future microbiology Feb, 2012 | Pubmed ID: 22324987
Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: extending towards the β-exosite.
Bioorganic & medicinal chemistry letters Jun, 2012 | Pubmed ID: 22542019
Contrasting effects of d-methamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxypyrovalerone, and 4-methylmethcathinone on wheel activity in rats.
Drug and alcohol dependence Nov, 2012 | Pubmed ID: 22664136
Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats.
PloS one , 2012 | Pubmed ID: 22952999
Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats.
Addiction biology Sep, 2013 | Pubmed ID: 23363010
Microsphere-based immunoassay for the detection of azaspiracids.
Analytical biochemistry Nov, 2013 | Pubmed ID: 24215909