Corrado Poggesi

Relaxation kinetics following sudden Ca(2+) reduction in single myofibrils from skeletal muscle.

Sarcomeric determinants of striated muscle relaxation kinetics.

Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.

Myofilament calcium sensitivity does not affect cross-bridge activation-relaxation kinetics.

Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium.

Spatially-compressed cardiac myofilament models generate hysteresis that is not found in real muscle.

Myofilament protein gene mutation screening and outcome of patients with hypertrophic cardiomyopathy.

Thin filament Ca2+ binding properties and regulatory unit interactions alter kinetics of tension development and relaxation in rabbit skeletal muscle.

The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils.

Insights into the kinetics of Ca2+-regulated contraction and relaxation from myofibril studies.

Developmental origins of hypertrophic cardiomyopathy phenotypes: a unifying hypothesis.

Susceptibility of isolated myofibrils to in vitro glutathionylation: Potential relevance to muscle functions.

Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.

Mechanical and energetic consequences of HCM-causing mutations.

Extraction and replacement of the tropomyosin-troponin complex in isolated myofibrils.

Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle.

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Patterns of disease progression in hypertrophic cardiomyopathy: an individualized approach to clinical staging.

α-Tropomyosin with a D175N or E180G mutation in only one chain differs from tropomyosin with mutations in both chains.

Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy.

Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations.

Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy.

Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy.

Chronic atrial fibrillation alters the functional properties of If in the human atrium.

Response to letter regarding article, "Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy".

Clusters of bound Ca(2+) initiate contraction in fast skeletal muscle.

Muscle dysfunction in hypertrophic cardiomyopathy: What is needed to move to translation?

Regulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatment.