Takashi Sakurai

The decrease of the cytoskeleton tubulin follows the decrease of the associating molecular chaperone alphaB-crystallin in unloaded soleus muscle atrophy without stretch.

Association between perceived social support and Th1 dominance.

Mononuclear five-coordinate molybdenum(IV) and -(V) monosulfide complexes coordinated with dithiolene ligands: reversible redox of Mo(V)/Mo(IV) and irreversible dimerization of [MoVS]- cores to a dinuclear [MoV2(mu-S)2]2- Core.

Ray tracing analysis of overlapping objects in refraction contrast imaging.

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.

[Cognitive dysfunction and dementia associated with elderly diabetes].

Neuroprotective effect of D-fructose-1,6-bisphosphate against beta-amyloid induced neurotoxicity in rat hippocampal organotypic slice culture: involvement of PLC and MEK/ERK signaling pathways.

Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus Japanese elderly diabetes intervention trial (J-EDIT).

Impaired response of perforating arteries to hypercapnia in chronic hyperglycemia.

Reversible sulfurization-desulfurization of tungsten bis(dithiolene) complexes.

In vivo X-ray angiography in the mouse brain using synchrotron radiation.

Association between diastolic blood pressure and lower hemoglobin A1C and frontal brain atrophy in elderly subjects with diabetes mellitus.

Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice.

[Expected role of professional geriatric physicians in education for geriatric medicine].

Quantification of distension in rat cerebral perforating arteries.

Carotid artery occlusion and collateral circulation in C57Black/6J mice detected by synchrotron radiation microangiography.

The molecular chaperone HSP47 rapidly senses gravitational changes in myoblasts.

[Group B streptococcal vertebral osteomyelitis following superficial suppurative thrombophlebitis].

Factors associated with lower Mini Mental State Examination scores in elderly Japanese diabetes mellitus patients.

Effects of human apolipoprotein E isoforms on the amyloid beta-protein concentration and lipid composition in brain low-density membrane domains.

Molecular basis of the shish-kebab morphology in polymer crystallization.

Differential mini-mental state examination profiles of older people with diabetes mellitus with early Alzheimer's disease.

BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit.

Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity.

In vivo cerebral artery microangiography in rat and mouse using synchrotron radiation imaging system.

[Advanced fluorescence microscopes for future work].

Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production.

Synthesis of 5''-branched derivatives of cyclic ADP-carbocyclic-ribose, a potent Ca2+-mobilizing agent: The first antagonists modified at the N1-ribose moiety.

[A case of elderly onset loss of consciousness due to bacterial meningitis and subsequent vasculitis].

Loss of CO2-induced distensibility in cerebral arteries with chronic hypertension or vasospasm after subarachnoid hemorrhage.

The double-edged effect of insulin on the neuronal cell death associated with hypoglycemia on the hippocampal slice culture.

Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.

Dilation of perforating arteries in rat brain in response to systemic hypotension is more sensitive and pronounced than that of pial arterioles: simultaneous visualization of perforating and cortical vessels by in-vivo microangiography.

Quantitative evaluation of bone resorption activity of osteoclast-like cells by measuring calcium phosphate resorbing area using incubator-facilitated and video-enhanced microscopy.

Mutant SOD1 impairs axonal transport of choline acetyltransferase and acetylcholine release by sequestering KAP3.

Significant roles of microtubules in mature striated muscle deduced from the correlation between tubulin and its molecular chaperone alphaB-crystallin in rat muscles.

Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.

Hasegawa Dementia Scale - revised, for screening of early Alzheimer's disease in the elderly with type 2 diabetes.

The temporomandibular joint in a rheumatoid arthritis patient after orthodontic treatment.

Protective effect of lecithinized SOD on reactive oxygen species-induced xerostomia.

Age-associated increase in abdominal obesity and insulin resistance, and usefulness of AHA/NHLBI definition of metabolic syndrome for predicting cardiovascular disease in Japanese elderly with type 2 diabetes mellitus.

Association of higher carbohydrate intake with depressive mood in elderly diabetic women.

Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system.

Education of lifestyle risk factors associated with dementia likely to help primary care physicians to improve consultation for elderly people with dementia.

Intravital oxygen radical imaging in normal and ischemic rat cortex.

Tissue stiffness induced by prolonged immobilization of the rat knee joint and relevance of AGEs (pentosidine).

Amyloid-β neurotoxicity restricts glucose window for neuronal survival in rat hippocampal slice cultures.

Usefulness of 18F-fluorodeoxyglucose positron emission tomography for diagnosis of asymptomatic giant cell arteritis in a patient with Alzheimer's disease.

Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes.

Causes of decreased activity of daily life in elderly patients who need daily living care.

Targets of the peroxisome proliferator-activated receptor γ agonist trials for the prevention of Alzheimer disease.

The macrophage-mediated effects of the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone attenuate tactile allodynia in the early phase of neuropathic pain development.

Basic helix-loop-helix transcription factor DEC1 negatively regulates cyclin D1.

Effects of insulin and amyloid β(1-42) oligomers on glucose incorporation and mitochondrial function in cultured rat hippocampal neurons.

[Incretin analogues as a novel treatment strategy for Alzheimer's disease].

Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts.

Practical method to derive nonlinear response functions of cameras for scientific imaging.

[Glucose intolerance and dementia].

Lidocaine attenuates the development of diabetic-induced tactile allodynia by inhibiting microglial activation.

Fucoidan suppresses endocytosis in cultured HeLa cells.

Role of amino-terminal half of the S4-S5 linker in type 1 ryanodine receptor (RyR1) channel gating.

[Discussion meeting on the collaboration network between general practitioners and specialists for the diagnosis and management of patients with dementia].

Predictive factors for hospitalized and institutionalized care-giving of the aged patients with diabetes mellitus in Japan.

Laminin α1 is essential for mouse cerebellar development.

Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function.

Long-term multiple risk factor interventions in Japanese elderly diabetic patients: the Japanese Elderly Diabetes Intervention Trial--study design, baseline characteristics and effects of intervention.

Non-high-density lipoprotein cholesterol: an important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients.

Relations of nutritional intake to age, sex and body mass index in Japanese elderly patients with type 2 diabetes: the Japanese Elderly Diabetes Intervention Trial.

Optimal energy distribution of carbohydrate intake for Japanese elderly patients with type 2 diabetes: the Japanese Elderly Intervention Trial.

Effects of total and green vegetable intakes on glycated hemoglobin A1c and triglycerides in elderly patients with type 2 diabetes mellitus: the Japanese Elderly Intervention Trial.

Dietary pattern and mortality in Japanese elderly patients with type 2 diabetes mellitus: does a vegetable- and fish-rich diet improve mortality? An explanatory study.

Lower physical activity, but not excessive calorie intake, is associated with metabolic syndrome in elderly with type 2 diabetes mellitus: the Japanese Elderly Diabetes Intervention Trial.

Lower physical activity is a strong predictor of cardiovascular events in elderly patients with type 2 diabetes mellitus beyond traditional risk factors: the Japanese Elderly Diabetes Intervention Trial.

Effective prevention of cardiovascular disease and diabetes-related events with atorvastatin in Japanese elderly patients with type 2 diabetes mellitus: adjusting for treatment changes using a marginal structural proportional hazards model and a rank-preserving structural failure time model.

Risk factors associated with cognitive decline in the elderly with type 2 diabetes: baseline data analysis of the Japanese Elderly Diabetes Intervention Trial.

Risk factors associated with cognitive decline in the elderly with type 2 diabetes: pooled logistic analysis of a 6-year observation in the Japanese Elderly Diabetes Intervention Trial.

Risk factors for a 6-year decline in physical disability and functional limitations among elderly people with type 2 diabetes in the Japanese Elderly Diabetes Intervention Trial.

Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: sub-analysis of the Japanese Elderly Diabetes Intervention Trial.

Pyruvate prevents the inhibition of the long-term potentiation induced by amyloid-β through protein phosphatase 2A inactivation.

Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.

Transplantation of side population cells restores the function of damaged exocrine glands through clusterin.

Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system.

Label-free characterization of living human induced pluripotent stem cells by subcellular topographic imaging technique using full-field quantitative phase microscopy coupled with interference reflection microscopy.

A warning index used in prescreening for Alzheimer's disease, based on self-reported cognitive deficits and vascular risk factors for dementia in elderly patients with type 2 diabetes.

[Dementia in diabetes mellitus: preventive strategy].

Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi.

Usefulness of running wheel for detection of congestive heart failure in dilated cardiomyopathy mouse model.

Treatment of salivary gland hypofunction by transplantation with dental pulp cells.

Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma.

Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger.

Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenance.

[Risks for impaired daily life function in the elderly with type 2 diabetes in Japan].

[Metabolic syndrome and impaired daily life function in the elderly].

[Simple screening test using instrumental activities of daily living to find early stage of dementia].

Large-scale cell production of stem cells for clinical application using the automated cell processing machine.

Functional cooperation of metabotropic adenosine and glutamate receptors regulates postsynaptic plasticity in the cerebellum.

Axillary reverse mapping using fluorescence imaging is useful for identifying the risk group of postoperative lymphedema in breast cancer patients undergoing sentinel node biopsies.

Regional white matter lesions predict falls in patients with amnestic mild cognitive impairment and Alzheimer's disease.

[Cognitive decline in elderly individuals with type 2 diabetes mellitus].

Evaluation of silicon nitride as a substrate for culture of PC12 cells: an interfacial model for functional studies in neurons.

Assembly of the cochlear gap junction macromolecular complex requires connexin 26.

Inter-cellular exchange of cellular components via VE-cadherin-dependent trans-endocytosis.

Developing an interdisciplinary program of educational support for early-stage dementia patients and their family members: an investigation based on learning needs and attitude changes.

Factors associated with increased caregivers' burden in several cognitive stages of Alzheimer's disease.

Effect of cerumen impaction on hearing and cognitive functions in Japanese older adults with cognitive impairment.

Differential subtypes of diabetic older adults diagnosed with Alzheimer's disease.

Left ventricular diastolic dysfunction is associated with cerebral white matter lesions (leukoaraiosis) in elderly patients without ischemic heart disease and stroke.

Association of grip strength and related indices with independence of activities of daily living in older adults, investigated by a newly-developed grip strength measuring device.

Cell-to-cell propagation of intracellular signals fluorescently visualized with acridine orange in the gastric glands of guinea pigs.

Two-dimensional microchemical observation of mast cell biogenic amine release as monitored by a 128 × 128 array-type charge-coupled device ion image sensor.

Mg(2+)- and ATP-dependent inhibition of transient receptor potential melastatin 7 by oxidative stress.

[Preventive strategy for cognitive decline in elderly with diabetes mellitus].