Kazuhiro Aoki

The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.

Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein.

Three-dimensional characterization of osteoclast bone-resorbing activity in the resorption lacunae.

Effect of recombinant human fibroblast growth factor-2 on bone formation in rabbit mandibular distraction models using beta-tricalcium phosphate.

IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.

Amount of bone lengthening affects blood flow recovery and bone mineralization after distraction osteogenesis in a canine cleft palate model.

Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle.

Neural-specific α3-fucosylation of N-linked glycans in the Drosophila embryo requires fucosyltransferase A and influences developmental signaling associated with O-glycosylation.

Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.

Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice.

The glycomics of glycan glucuronylation in Drosophila melanogaster.

Spatiotemporal regulation of small GTPases as revealed by probes based on the principle of Förster Resonance Energy Transfer (FRET): Implications for signaling and pharmacology.

Revolving movement of a dynamic cluster of actin filaments during mitosis.

A novel underuse model shows that inactivity but not ovariectomy determines the deteriorated material properties and geometry of cortical bone in the tibia of adult rats.

Sugar-free frosting, a homolog of SAD kinase, drives neural-specific glycan expression in the Drosophila embryo.

Glycomic analyses of mouse models of congenital muscular dystrophy.

A xylosylphosphotransferase of Cryptococcus neoformans acts in protein O-glycan synthesis.

The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor-α-induced bone resorption lacunae on mouse calvariae.

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.

Processive phosphorylation of ERK MAP kinase in mammalian cells.

Development of an optimized backbone of FRET biosensors for kinases and GTPases.

Stable expression of FRET biosensors: a new light in cancer research.

Selective inhibition of NF-κB suppresses bone invasion by oral squamous cell carcinoma in vivo.

Accumulation of p100, a precursor of NF-κB2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice.

A structural modulator of tumor necrosis factor type 1 receptor promotes bone formation under lipopolysaccharide-induced inflammation in a murine tooth extraction model.

FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells.

Peptide-based delivery to bone.

[Computational simulation based on experimentally-determined kinetic parameters in signal transduction].

Biosynthesis of the major brain gangliosides GD1a and GT1b.

CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction.

Female distance runners show a different response to post-workout consumption of wheat gluten hydrolysate compared to their male counterparts.

Post-training consumption of wheat gluten hydrolysate suppresses the delayed onset of muscle injury in soccer players.

Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis.

Porcine sperm bind to specific 6-sialylated biantennary glycans to form the oviduct reservoir.

Stage-specific expression and antigenicity of glycoprotein glycans isolated from the human liver fluke, Opisthorchis viverrini.

Stimulation of bone formation in cortical bone of mice treated with a receptor activator of nuclear factor-κB ligand (RANKL)-binding peptide that possesses osteoclastogenesis inhibitory activity.

Disruption of NF-κB1 prevents bone loss caused by mechanical unloading.

Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: basis of biosensor construction, live imaging, and image processing.

p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.

A quantitative model of ERK MAP kinase phosphorylation in crowded media.

Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.

Effect of yellow-tinted lenses on visual attributes related to sports activities.

Unique distribution of deep groundwater bacteria constrained by geological setting.

Analyses of associations between reactive oxygen metabolites and antioxidant capacity and related factors among healthy adolescents.

Occurrence and potential activity of denitrifiers and methanogens in groundwater at 140 m depth in Pliocene diatomaceous mudstone of northern Japan.

Osteoclast formation and differentiation: an overview.

In-gel β-elimination and aqueous-organic partition for improved O- and sulfoglycomics.

A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation.

Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I.

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation.

Development of a FRET biosensor with high specificity for Akt.

Discrimination between Adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis.

TGF-β in dentin matrix extract induces osteoclastogenesis in vitro.

Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1.

Variability of factors driving spatial and temporal dispersion in river plume and Chattonella antiqua bloom in the Yatsushiro Sea, Japan.

Wheat gluten hydrolysate affects race performance in the triathlon.

Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs.

Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction.

Cardiorespiratory fitness and the incidence of type 2 diabetes: a cohort study of Japanese male athletes.

NF-κB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation.

Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions.

Characterization of pulp and follicle stem cells from impacted supernumerary maxillary incisors.

Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.

Qrator: A web-based curation tool for glycan structures.

The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma.