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Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.
The Journal of experimental medicine Dec, 2004 | Pubmed ID: 15596525
Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak.
American journal of physiology. Cell physiology Apr, 2006 | Pubmed ID: 16338970
Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.
Advances in experimental medicine and biology , 2006 | Pubmed ID: 17249564
MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin.
Advances in experimental medicine and biology , 2006 | Pubmed ID: 17249615
Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17620600
Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 18188966
Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function.
Ophthalmic research , 2008 | Pubmed ID: 18421224
TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness.
American journal of human genetics Nov, 2009 | Pubmed ID: 19896113
Mertk in daily retinal phagocytosis: a history in the making.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20238011
EYS is a major gene for rod-cone dystrophies in France.
Human mutation May, 2010 | Pubmed ID: 20333770
Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.
Investigative ophthalmology & visual science Jan, 2011 | Pubmed ID: 20811066
In vitro differentiation of retinal pigment epithelium from adult retinal stem cells.
Pigment cell & melanoma research Feb, 2011 | Pubmed ID: 21232026
Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin.
Free radical biology & medicine Feb, 2012 | Pubmed ID: 22178979
On your marks…get bound…internalize!
Advances in experimental medicine and biology , 2012 | Pubmed ID: 22183398
Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin.
Biology of the cell / under the auspices of the European Cell Biology Organization Jan, 2012 | Pubmed ID: 22289110
Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis.
Cellular reprogramming Jun, 2013 | Pubmed ID: 23663011
Disease-causing mutations in BEST1 gene are associated with altered sorting of bestrophin-1 protein.
International journal of molecular sciences , 2013 | Pubmed ID: 23880862
The Signalling Role of the avβ5-Integrin Can Impact the Efficacy of AAV in Retinal Gene Therapy.
Pharmaceuticals (Basel, Switzerland) , 2012 | Pubmed ID: 24281556
Animal Models, in "The Quest to Decipher RPE Phagocytosis".
Advances in experimental medicine and biology , 2014 | Pubmed ID: 24664683
From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2014 | Pubmed ID: 24912154
Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.
The American journal of pathology Oct, 2014 | Pubmed ID: 25111227
INSERM, U968
Institut de la Vision
CNRS, UMR_7210
Célia Parinot1,2,3,
Quentin Rieu1,2,3,
Jonathan Chatagnon1,2,3,
Silvia C. Finnemann4,
Emeline F. Nandrot1,2,3
1, INSERM, U968,
2Sorbonne Universités, UPMC Paris 06, UMR_S 968, Institut de la Vision,
3, CNRS, UMR_7210,
4Department of Biological Sciences, Center for Cancer, Genetic Diseases and Gene Regulation, Fordham University
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