Department of Pathology
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Two-step upflow anaerobic sludge bed system for sewage treatment under subtropical conditions with posttreatment in waste stabilization ponds.
Applied biochemistry and biotechnology Apr-Jun, 2003 | Pubmed ID: 12794292
Comparative isoschizomer profiling of cytosine methylation: the HELP assay.
Genome research Aug, 2006 | Pubmed ID: 16809668
Smad1 and Smad5 differentially regulate embryonic hematopoiesis.
Blood Dec, 2007 | Pubmed ID: 17761518
CG dinucleotide clustering is a species-specific property of the genome.
Nucleic acids research , 2007 | Pubmed ID: 17932072
An integrative genomic and epigenomic approach for the study of transcriptional regulation.
PloS one , 2008 | Pubmed ID: 18365023
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Cancer research Sep, 2008 | Pubmed ID: 18794111
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.
Blood Mar, 2009 | Pubmed ID: 19168792
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19277580
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers.
Nucleic acids research Jul, 2009 | Pubmed ID: 19386619
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation.
Blood Oct, 2009 | Pubmed ID: 19652201
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.
Cancer cell Jan, 2010 | Pubmed ID: 20060365
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.
Blood Jun, 2010 | Pubmed ID: 20215641
HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20217579
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Cancer research Jul, 2010 | Pubmed ID: 20587527
Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.
Blood Jan, 2011 | Pubmed ID: 20855866
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
The Journal of clinical investigation Nov, 2010 | Pubmed ID: 21041953
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Cancer cell Dec, 2010 | Pubmed ID: 21130701
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Cancer cell Jul, 2011 | Pubmed ID: 21723200
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation.
Blood Sep, 2011 | Pubmed ID: 21828137
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Nature Mar, 2012 | Pubmed ID: 22343901
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
The New England journal of medicine Mar, 2012 | Pubmed ID: 22417203
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia.
Blood Jun, 2012 | Pubmed ID: 22490330
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia.
PLoS genetics , 2012 | Pubmed ID: 22737091
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.
Nature Aug, 2012 | Pubmed ID: 22763442
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900.
Blood Sep, 2012 | Pubmed ID: 22855599
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.
Cancer cell Aug, 2012 | Pubmed ID: 22897850
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.
Nature genetics Nov, 2012 | Pubmed ID: 23001125
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles.
Genome biology Oct, 2012 | Pubmed ID: 23034086
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.
The Journal of clinical investigation Dec, 2012 | Pubmed ID: 23160200
Interpreting new molecular genetics in myelodysplastic syndromes.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2012 | Pubmed ID: 23233561
Notch activation inhibits AML growth and survival: a potential therapeutic approach.
The Journal of experimental medicine Feb, 2013 | Pubmed ID: 23359069
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.
Nature immunology May, 2013 | Pubmed ID: 23563689
Understanding and utilizing new molecular genetics in MDS.
Clinical advances in hematology & oncology : H&O Feb, 2013 | Pubmed ID: 23598913
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.
The Journal of clinical investigation Jul, 2013 | Pubmed ID: 23921123
Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes.
Blood Oct, 2013 | Pubmed ID: 23980066
Epigenetic roles of MLL oncoproteins are dependent on NF-κB.
Cancer cell Oct, 2013 | Pubmed ID: 24054986
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.
Cell reports Dec, 2013 | Pubmed ID: 24332853
Microsphere-based multiplex analysis of DNA methylation in acute myeloid leukemia.
The Journal of molecular diagnostics : JMD Mar, 2014 | Pubmed ID: 24373919
Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Apr, 2014 | Pubmed ID: 24663049
Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling.
Blood May, 2014 | Pubmed ID: 24668493
Epigenetic deregulation in myeloid malignancies.
Translational research : the journal of laboratory and clinical medicine Jan, 2015 | Pubmed ID: 24813528
MethylSig: a whole genome DNA methylation analysis pipeline.
Bioinformatics (Oxford, England) Sep, 2014 | Pubmed ID: 24836530
Validation of DNA methylation to predict outcome in acute myeloid leukemia by use of xMELP.
Clinical chemistry Jan, 2015 | Pubmed ID: 25348669
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Cell reports Dec, 2014 | Pubmed ID: 25482556
Plasticity of DNA methylation in a nerve injury model of pain.
Epigenetics : official journal of the DNA Methylation Society Jan, 2015 | Pubmed ID: 25621511
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.
The Journal of clinical investigation Feb, 2015 | Pubmed ID: 25664853