Nicholas E. Leadbeater

A study of the ionic liquid mediated microwave heating of organic solvents.

Microencapsulated VO(acac)2: preparation and use in allylic alcohol epoxidation.

Polymer-bound 1-aryl-3-alkyltriazenes as modular ligands for catalysis. Part 1: synthesis and metal coordination.

Polymer-bound 1-aryl-3-alkyltriazenes as modular ligands for catalysis. Part 2: screening immobilized metal complexes for catalytic activity.

Ligand-free palladium catalysis of the Suzuki reaction in water using microwave heating.

Preparation of polymer-supported ligands and metal complexes for use in catalysis.

Polymer-supported metal-phosphine complexes for use as catalysts or linkers in medicinally-oriented organic synthesis.

Rapid and amenable suzuki coupling reaction in water using microwave and conventional heating.

Transition-metal-free Suzuki-type coupling reactions.

Transition-metal-free Suzuki-type coupling reactions: scope and limitations of the methodology.

Rapid cyanation of aryl iodides in water using microwave promotion.

First examples of transition-metal free Sonogashira-type couplings.

Rapid, easy cyanation of aryl bromides and chlorides using nickel salts in conjunction with microwave promotion.

Microwave-assisted Mannich-type three-component reactions.

A reassessment of the transition-metal free suzuki-type coupling methodology.

Microwave-promoted Heck coupling using ultralow metal catalyst concentrations.

Suzuki coupling of aryl chlorides with phenylboronic acid in water, using microwave heating with simultaneous cooling.

Fast, easy, clean chemistry by using water as a solvent and microwave heating: the Suzuki coupling as an illustration.

Real-time monitoring of microwave-promoted Suzuki coupling reactions using in situ Raman spectroscopy.

Real-time monitoring of microwave-promoted organometallic ligand-substitution reactions using in situ Raman spectroscopy.

Alkoxycarbonylation of aryl iodides using gaseous carbon monoxide and pre-pressurized reaction vessels in conjunction with microwave heating.

Using in situ Raman monitoring as a tool for rapid optimisation and scale-up of microwave-promoted organic synthesis: esterification as an example.

Probing the effects of microwave irradiation on enzyme-catalysed organic transformations: the case of lipase-catalysed transesterification reactions.

Microwave energy: a versatile tool for the biosciences.

In situ Raman spectroscopy as a probe for the effect of power on microwave-promoted Suzuki coupling reactions.

Use of Raman spectroscopy as a tool for in situ monitoring of microwave-promoted reactions.

Microwave-promoted insertion of Group 10 metals into free base porphyrins and chlorins: scope and limitations.

Preparation of nonsymmetrically substituted stilbenes in a one-pot two-step heck strategy using ethene as a reagent.

Use of Raman spectroscopy as an in situ tool to obtain kinetic data for organic transformations.

Palladium-catalyzed decarboxylative coupling of aromatic acids with aryl halides or unactivated arenes using microwave heating.

Testing the validity of microwave-interfaced, in situ Raman spectroscopy as a tool for kinetic studies.

Palladium-catalyzed synthesis of diarylmethanes: exploitation of carbanionic leaving groups.

Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating.

Probing "microwave effects" using Raman spectroscopy.

In situ reaction monitoring of microwave-mediated reactions using IR spectroscopy.

Cross coupling: When is free really free?

Titanium-catalyzed esterification and transesterification reactions facilitated using microwave heating.

Continuous-flow, palladium-catalysed alkoxycarbonylation reactions using a prototype reactor in which it is possible to load gas and heat simultaneously.

Access to dienophilic ene-triketone synthons by oxidation of diketones with an oxoammonium salt.

A Weinreb amide approach to the synthesis of trifluoromethylketones.

Oxidation of α-trifluoromethyl alcohols using a recyclable oxoammonium salt.

Ask the experts: the challenges and benefits of flow chemistry to optimize drug development.

The central role of chemistry in 'quality by design' approaches to drug development.

Synthesis of 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate and 4-acetamido-(2,2,6,6-tetramethyl-piperidin-1-yl)oxyl and their use in oxidative reactions.

Oxidative esterification of aldehydes using a recyclable oxoammonium salt.

Raman spectroscopy as a tool for monitoring mesoscale continuous-flow organic synthesis: Equipment interface and assessment in four medicinally-relevant reactions.

Trifluoromethyl ketones: properties, preparation, and application.

Opening an Aladdin's cave: the Suzuki coupling in a room-temperature ionic liquid.

Methylenation of perfluoroalkyl ketones using a Peterson olefination approach.

Access to nitriles from aldehydes mediated by an oxoammonium salt.

Oxidative cleavage of allyl ethers by an oxoammonium salt.

Toward a Unified Mechanism for Oxoammonium Salt-Mediated Oxidation Reactions: A Theoretical and Experimental Study Using a Hydride Transfer Model.