Department of Cell Biology and Anatomy,
College of Medicine,
Department of Cell Biology and Anatomy, College of Medicine
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Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis.
Cancer letters Mar, 2002 | Pubmed ID: 11825660
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis.
Mutation research Jun, 2002 | Pubmed ID: 12052432
Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients.
Annals of surgical oncology Jun, 2002 | Pubmed ID: 12052764
Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Carcinogenesis Dec, 2002 | Pubmed ID: 12507930
Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis.
Chemico-biological interactions Mar, 2003 | Pubmed ID: 12606154
Perils of immunohistochemistry: variability in staining specificity of commercially available COX-2 antibodies on human colon tissue.
Digestive diseases and sciences Jan, 2003 | Pubmed ID: 12645811
Deoxycholate, an endogenous tumor promoter and DNA damaging agent, modulates BRCA-1 expression in apoptosis-sensitive epithelial cells: loss of BRCA-1 expression in colonic adenocarcinomas.
Nutrition and cancer , 2003 | Pubmed ID: 12925308
A proteomic study of resistance to deoxycholate-induced apoptosis.
Carcinogenesis May, 2004 | Pubmed ID: 14729586
Increased expression and secretion of interleukin-6 in patients with Barrett's esophagus.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2004 | Pubmed ID: 15041721
Apoptosis resistance in Barrett's esophagus: ex vivo bioassay of live stressed tissues.
The American journal of gastroenterology Feb, 2005 | Pubmed ID: 15667503
Assessment of apoptosis by immunohistochemical markers compared to cellular morphology in ex vivo-stressed colonic mucosa.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Feb, 2005 | Pubmed ID: 15684335
Crypt-restricted loss and decreased protein expression of cytochrome C oxidase subunit I as potential hypothesis-driven biomarkers of colon cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Sep, 2005 | Pubmed ID: 16172211
Identification of S-nitrosylated proteins after chronic exposure of colon epithelial cells to deoxycholate.
Proteomics Mar, 2006 | Pubmed ID: 16404723
A survey of psychiatric residency directors on current priorities and preparation for public-sector care.
Psychiatric services (Washington, D.C.) Feb, 2006 | Pubmed ID: 16452702
Recruiting and rewarding faculty for medical student teaching.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry Mar-Apr, 2006 | Pubmed ID: 16609118
Unique dietary-related mouse model of colitis.
Inflammatory bowel diseases Apr, 2006 | Pubmed ID: 16633050
Reduced Pms2 expression in non-neoplastic flat mucosa from patients with colon cancer correlates with reduced apoptosis competence.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry Jun, 2006 | Pubmed ID: 16785784
Pathogenesis of diarrhea in the adult: diagnostic challenges and life-threatening conditions.
European journal of gastroenterology & hepatology Oct, 2006 | Pubmed ID: 16957509
Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett's oesophagus.
Gut Jun, 2007 | Pubmed ID: 17145738
Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles.
Digestive diseases and sciences Mar, 2007 | Pubmed ID: 17253130
Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2007 | Pubmed ID: 17875759
Scientific misconduct and liability for the acts of others.
Medicine and law Sep, 2007 | Pubmed ID: 17970247
What is scientific misconduct, who has to (dis)prove it, and to what level of certainty?
Medicine and law Sep, 2007 | Pubmed ID: 17970248
A novel dietary-related model of esophagitis and Barrett's esophagus, a premalignant lesion.
Nutrition and cancer , 2007 | Pubmed ID: 18001217
Field defects in progression to gastrointestinal tract cancers.
Cancer letters Feb, 2008 | Pubmed ID: 18164807
Normal pressure hydrocephalus presenting as Othello syndrome: case presentation and review of the literature.
The American journal of psychiatry Sep, 2008 | Pubmed ID: 18765494
Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma.
The American journal of gastroenterology Feb, 2009 | Pubmed ID: 19174784
Bile acids as endogenous etiologic agents in gastrointestinal cancer.
World journal of gastroenterology : WJG Jul, 2009 | Pubmed ID: 19610133
Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.
Journal of toxicology , 2009 | Pubmed ID: 20130808
Exposure of mouse colon to dietary bile acid supplement induces sessile adenomas.
Inflammatory bowel diseases May, 2010 | Pubmed ID: 20135625
Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
Nutrition and cancer , 2010 | Pubmed ID: 20661832
Response to the presidential address.
The American journal of psychiatry Oct, 2010 | Pubmed ID: 20889662
Cancer and age related colonic crypt deficiencies in cytochrome c oxidase I.
World journal of gastrointestinal oncology Dec, 2010 | Pubmed ID: 21191537
Carcinogenicity of deoxycholate, a secondary bile acid.
Archives of toxicology Aug, 2011 | Pubmed ID: 21267546
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis.
Clinical and experimental gastroenterology , 2008 | Pubmed ID: 21677822
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.
Clinical and experimental gastroenterology , 2011 | Pubmed ID: 21753893
Burnout during residency training: a literature review.
Journal of graduate medical education Dec, 2009 | Pubmed ID: 21975985
Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis.
Clinical and experimental gastroenterology , 2011 | Pubmed ID: 22162927
Teaching "global mental health": psychiatry residency directors' attitudes and practices regarding international opportunities for psychiatry residents.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry Nov, 2011 | Pubmed ID: 22193740
Huy Nguyen1,
Cristy Loustaunau1,
Alexander Facista1,
Lois Ramsey1,
Nadia Hassounah1,
Hilary Taylor1,
Robert Krouse2,3,
Claire M. Payne1,4,
V. Liana Tsikitis3,
Steve Goldschmid5,
Bhaskar Banerjee5,
Rafael F. Perini5,
Carol Bernstein1
1Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson,
2Southern Arizona Veterans Affairs Health Care System, Tucson, AZ,
3Department of Surgery, College of Medicine, University of Arizona, Tucson,
4Biomedical Diagnostics and Research, Tucson, AZ,
5Department of Medicine, College of Medicine, University of Arizona, Tucson