Jacques Robert

Minor histocompatibility antigen-specific MHC-restricted CD8 T cell responses elicited by heat shock proteins.

[New concepts for the study of anticancer drug resistance].

Alterations in the expression of cytochrome c oxidase subunits in doxorubicin-resistant leukemia K562 cells.

Effects of paclitaxel, cyclophosphamide, ifosfamide, tamoxifen and cyclosporine on the metabolism of methoxymorpholinodoxorubicin in human liver microsomes.

Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines.

Determination of drug interactions occurring with the metabolic pathways of irinotecan.

Identification and characterization of Xenopus CD8+ T cells expressing an NK cell-associated molecule.

Evolution of heat shock protein and immunity.

Ontogeny of Xenopus NK cells in the absence of MHC class I antigens.

Signaling FcRgamma and TCRzeta subunit homologs in the amphibian Xenopus laevis.

Development and characterization of a model system to study amphibian immune responses to iridoviruses.

Multidrug resistance reversal agents.

Xenopus as an experimental model for studying evolution of hsp--immune system interactions.

Molecular determinants of the cytotoxicity of platinum compounds: the contribution of in silico research.

[Recent advances in pharmacogenomics in oncology].

Bacterial stimulation upregulates the surface expression of the stress protein gp96 on B cells in the frog Xenopus.

Cellular parameters predictive of the clinical response of colorectal cancers to irinotecan. A preliminary study.

Anti-tumor MHC class Ia-unrestricted CD8 T cell cytotoxicity elicited by the heat shock protein gp96.

Predicting drug response based on gene expression.

Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38.

CD91 up-regulates upon immune stimulation in Xenopus adult but not larval peritoneal leukocytes.

Phylogenetic conservation of gp96-mediated antigen-specific cellular immunity: new evidence from adoptive cell transfer in xenopus.

MS-209 Schering.

Adaptive immunity and histopathology in frog virus 3-infected Xenopus.

Quantification of the expression of multidrug resistance-related genes in human tumour cell lines grown with free doxorubicin or doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres.

Predicting drug response and toxicity based on gene polymorphisms.

Major improvement of the reference method of the French drug resistance network for P-glycoprotein detection in human haematological malignancies.

8-O-Azeloyl-14-benzoylaconine: a new alkaloid from the roots of Aconitum karacolicum Rapcs and its antiproliferative activities.

Experimental study of dexrazoxane-anthracycline combinations using the model of isolated perfused rat heart.

Generation of a long-lasting, protective, and neutralizing antibody response to the ranavirus FV3 by the frog Xenopus.

Mitochondrial localization and activity of P-glycoprotein in doxorubicin-resistant K562 cells.

Genetic polymorphisms of the XPG and XPD nucleotide excision repair genes in sarcoma patients.

A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte.

Structural phylogenetic analysis of activation-induced deaminase function.

A phase II study for the evaluation of quinine as a modulator of multidrug resistance in non-Hodgkin's lymphoma.

Relationships between genetic polymorphisms and anticancer drug cytotoxicity vis-à-vis the NCI-60 panel.

Characterization of primary and memory CD8 T-cell responses against ranavirus (FV3) in Xenopus laevis.

In vivo study of T-cell responses to skin alloantigens in Xenopus using a novel whole-mount immunohistology method.

Involvement of gene polymorphisms of thymidylate synthase in gene expression, protein activity and anticancer drug cytotoxicity using the NCI-60 panel.

Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505.

Functional analysis of the gene expression profiles of colorectal cancer cell lines in relation to oxaliplatin and cisplatin cytotoxicity.

Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene.

Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses.

Long-term and short-term models for studying anthracycline cardiotoxicity and protectors.

Postmating changes in cuticular chemistry and visual appearance in Ectatomma tuberculatum queens (Formicidae: Ectatomminae).

Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress.

Synthesis and antiproliferative activity of aryl- and heteroaryl-hydrazones derived from xanthone carbaldehydes.

[What is a targeted therapy? The view of the biologist].

Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development.

Xenopus laevis: a possible vector of Ranavirus infection?

Determination of ERCC2 Lys751Gln and GSTP1 Ile105Val gene polymorphisms in colorectal cancer patients: relationships with treatment outcome.

Phylogenetic conservation of glycoprotein 96 ability to interact with CD91 and facilitate antigen cross-presentation.

A chemotherapy-associated senescence bystander effect in breast cancer cells.

Protein arginine (N)-methyl transferase 7 (PRMT7) as a potential target for the sensitization of tumor cells to camptothecins.

In vivo and in vitro techniques for comparative study of antiviral T-cell responses in the amphibian Xenopus.

The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution.

Impact of EGFR gene polymorphisms on anticancer drug cytotoxicity in vitro.

[Biological bases for individualising prescriptions in oncology: the germline genome].

Xenopus, a unique comparative model to explore the role of certain heat shock proteins and non-classical MHC class Ib gene products in immune surveillance.

Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors.

Comparative and developmental study of the immune system in Xenopus.

Diversity of the FcR- and KIR-related genes in an amphibian Xenopus.

Tumorigenesis and anti-tumor immune responses in Xenopus.

Control of asthma in children: still unacceptable? A French cross-sectional study.

Isolation of a Latimeria menadoensis heat shock protein 70 (Lmhsp70) that has all the features of an inducible gene and encodes a functional molecular chaperone.

Involvement of gene polymorphisms of the folate pathway enzymes in gene expression and anticancer drug sensitivity using the NCI-60 panel as a model.

Towards real-time radiation therapy: GPU accelerated superposition/convolution.

Genome-wide transcriptional response of Silurana (Xenopus) tropicalis to infection with the deadly chytrid fungus.

The amphibians Xenopus laevis and Silurana tropicalis possess a family of activating KIR-related Immunoglobulin-like receptors.

Expression profiling the temperature-dependent amphibian response to infection by Batrachochytrium dendrobatidis.

Phylogeny, genomic organization and expression of lambda and kappa immunoglobulin light chain genes in a reptile, Anolis carolinensis.

Mass mortality associated with a frog virus 3-like Ranavirus infection in farmed tadpoles Rana catesbeiana from Brazil.

Patient geometry-driven information retrieval for IMRT treatment plan quality control.

Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis.

A shape relationship descriptor for radiation therapy planning.

The genome of the Western clawed frog Xenopus tropicalis.

Landau-Zener transitions in frozen pairs of Rydberg atoms.

Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates.

Data-driven approach to generating achievable dose-volume histogram objectives in intensity-modulated radiotherapy planning.

A statistical approach for achievable dose querying in IMRT planning.

Cytochrome P450 1B1 gene polymorphisms as predictors of anticancer drug activity: studies with in vitro models.

Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins.

Phylogenetic and developmental study of CD4, CD8 α and β T cell co-receptor homologs in two amphibian species, Xenopus tropicalis and Xenopus laevis.

Remarkable conservation of distinct nonclassical MHC class I lineages in divergent amphibian species.

The genus Xenopus as a multispecies model for evolutionary and comparative immunobiology of the 21st century.

ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.

ERCC5/XPG, ERCC1, and BRCA1 gene status and clinical benefit of trabectedin in patients with soft tissue sarcoma.

Real-time dose computation: GPU-accelerated source modeling and superposition/convolution.

[General overview on DNA repair].

Role of DNA repair gene polymorphisms in the efficiency of platinum-based adjuvant chemotherapy for non-small cell lung cancer.

Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis.

Encapsulation of docetaxel into PEGylated gold nanoparticles for vectorization to cancer cells.

Improved knockout methodology reveals that frog virus 3 mutants lacking either the 18K immediate-early gene or the truncated vIF-2alpha gene are defective for replication and growth in vivo.

"Ranaviruses: an emerging threat to ectothermic vertebrates" report of the First International Symposium on Ranaviruses, Minneapolis MN July 8, 2011.

Optimized transgenesis in Xenopus laevis/gilli isogenetic clones for immunological studies.

7β-Hydroxycholesterol-induced energy stress leads to sequential opposing signaling responses and to death of C6 glioblastoma cells.

[Tyrosine kinase inhibitors].

Antiviral immunity in amphibians.

Absence of transcriptomic signature of response to chemotherapy in metastatic colorectal carcinoma patients.