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Titus Family Department of Clinical Pharmacy and Pharmaceutical Economics & Policy
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Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17517895
A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1.
Molecular cell Mar, 2008 | Pubmed ID: 18342604
Allosteric interactions direct binding and phosphorylation of ASF/SF2 by SRPK1.
Biochemistry Dec, 2009 | Pubmed ID: 19886675
The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs.
Nucleic acids research Nov, 2011 | Pubmed ID: 21852328
Ivermectin reduces alcohol intake and preference in mice.
Neuropharmacology Aug, 2012 | Pubmed ID: 22465817
Multiday administration of ivermectin is effective in reducing alcohol intake in mice at doses shown to be safe in humans.
Neuroreport Sep, 2014 | Pubmed ID: 25004078
Oral delivery of ivermectin using a fast dissolving oral film: Implications for repurposing ivermectin as a pharmacotherapy for alcohol use disorder.
Alcohol (Fayetteville, N.Y.) Sep, 2015 | Pubmed ID: 26095588
Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder.
Neuropharmacology 02, 2017 | Pubmed ID: 27641072
Reduced expression of purinergic P2X4 receptors increases voluntary ethanol intake in C57BL/6J mice.
Alcohol (Fayetteville, N.Y.) May, 2018 | Pubmed ID: 29477921
Preclinical evaluation of avermectins as novel therapeutic agents for alcohol use disorders.
Psychopharmacology Jun, 2018 | Pubmed ID: 29500584
University of Southern California School of Pharmacy
University of Southern California
Nhat Huynh*,1,
Natalie Arabian*,1,
Dustin Lieu1,
Liana Asatryan1,
Daryl L. Davies1
1Titus Family Department of Clinical Pharmacy and Pharmaceutical Economics & Policy, University of Southern California School of Pharmacy
Natalie M Arabian*,1,
Daryl L Davies1
1Titus Family Department of Clinical Pharmacy and Pharmaceutical Economics & Policy, School of Pharmacy, University of Southern California
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