Stephen McLaughlin

Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding.

Stimulation of the weak ATPase activity of human hsp90 by a client protein.

Folding and stability of the ligand-binding domain of the glucocorticoid receptor.

A novel rapid single nucleotide polymorphism (SNP)-based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation.

Quantitative monitoring of BCR/ABL transcript during STI-571 therapy.

Retinal ganglion cells projecting to the dorsal raphe and lateral geniculate complex in Mongolian gerbils.

Expansion of tumor-specific CD8+ T cell clones in patients with relapsed myeloma after donor lymphocyte infusion.

How safe is adjuvant chemotherapy and radiotherapy for rectal cancer?

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform.

Gastrointestinal haemorrhage complicating small bowel neurofibromatosis.

Preoperative chemotherapy and radiotherapy for locally advanced rectal cancer.

A single-molecule method for the quantitation of microRNA gene expression.

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.

Re: Completion of therapy by Medicare patients with stage III colon cancer.

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.

Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46.

Rapid whole-genome mutational profiling using next-generation sequencing technologies.

A microRNA expression ratio defining the invasive phenotype in bladder tumors.

Re: Residual treatment disparities after oncology referral for rectal cancer.

Initial impact of Australia's National Bowel Cancer Screening Program.

A small-cell lung cancer genome with complex signatures of tobacco exposure.

Education and Imaging. Colonic perforation during 'virtual' CT colonography.

Mesenteric panniculitis: a diagnosis of exclusion.

The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes.

Mutational analysis reveals a single binding interface between RhoA and its effector, PRK1.

Electrostatic interactions involving the extreme C terminus of nuclear export factor CRM1 modulate its affinity for cargo.

Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology.

A comprehensively molecular haplotype-resolved genome of a European individual.

New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing.

Synthetic genetic polymers capable of heredity and evolution.

Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation.

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.

Second primary colorectal cancer in the era of prevalent screening and imaging.

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.

Novel Conserved Genotypes Correspond to Antibiotic Resistance Phenotypes of E. coli Clinical Isolates.

The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.

Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoB.

Fate of Cryptosporidium parvum oocysts within soil, water, and plant environment.

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.

Structure of the SAS-6 cartwheel hub from Leishmania major.

Expanded genetic codes in next generation sequencing enable decontamination and mitochondrial enrichment.

Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation.

Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors.

Molecular architecture and mechanism of the anaphase-promoting complex.

Outcomes in the surgical treatment of low rectal cancer: does neoadjuvant treatment equalize results?

Evolution of oligomeric state through allosteric pathways that mimic ligand binding.

Bayesian estimation of the multifractality parameter for image texture using a whittle approximation.

Hurt, tired and queasy: Specific variants in the ATPase domain of the TRAP1 mitochondrial chaperone are associated with common, chronic "functional" symptomatology including pain, fatigue and gastrointestinal dysmotility.

Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.

Atomic structure of the APC/C and its mechanism of protein ubiquitination.

The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity.

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer.

Neighborhood Factors During Adolescence: Modest Effects On Cardiovascular Risk, Small Impact On Obesity And Depression.

Identifying the dominant prostate cancer focal lesion using image analysis and planning of a simultaneous integrated stereotactic boost.

Identifying radiotherapy target volumes in brain cancer by image analysis.

Crystal structure of the Z-ring associated cell division protein ZapC from Escherichia coli.

INVITED REVIEW-IMAGE REGISTRATION IN VETERINARY RADIATION ONCOLOGY: INDICATIONS, IMPLICATIONS, AND FUTURE ADVANCES.

Lidar waveform based analysis of depth images constructed using sparse single-photon data.

Adaptive multimode signal reconstruction from time-frequency representations.