Institute of Cellular Therapeutics
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Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.
Diabetes Feb, 2002 | Pubmed ID: 11812742
Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes.
Cell transplantation , 2002 | Pubmed ID: 12099635
Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound.
Diabetes Aug, 2002 | Pubmed ID: 12145171
Production of alpha 1,3-galactosyltransferase-deficient pigs.
Science (New York, N.Y.) Jan, 2003 | Pubmed ID: 12493821
Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12524423
Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes.
Diabetes Feb, 2003 | Pubmed ID: 12540612
Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.
Stem cells (Dayton, Ohio) , 2003 | Pubmed ID: 12832692
Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity.
Diabetes Aug, 2003 | Pubmed ID: 12882913
Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-Timer fusion protein.
BioTechniques Oct, 2003 | Pubmed ID: 14579736
Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans.
Experimental diabesity research Jul-Sep, 2004 | Pubmed ID: 15512788
Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Nov, 2005 | Pubmed ID: 16212626
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes.
Diabetes Apr, 2006 | Pubmed ID: 16567506
Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2006 | Pubmed ID: 17015713
Modulatory role of DR4- to DQ8-restricted CD4 T-cell responses and type 1 diabetes susceptibility.
Diabetes Dec, 2006 | Pubmed ID: 17130492
Isolation outcome and functional characteristics of young and adult pig pancreatic islets for transplantation studies.
Xenotransplantation Jan, 2007 | Pubmed ID: 17214707
Suppression of memory CD8 T cell generation and function by tryptophan catabolism.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2007 | Pubmed ID: 17371982
Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels.
American journal of physiology. Endocrinology and metabolism Jul, 2007 | Pubmed ID: 17405830
Lipin1 regulation by estrogen in uterus and liver: implications for diabetes and fertility.
Endocrinology Aug, 2007 | Pubmed ID: 17463059
Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis.
Diabetes Sep, 2007 | Pubmed ID: 17596403
Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation.
Transplantation Aug, 2007 | Pubmed ID: 17700153
Suppression of autoimmune diabetes by soluble galectin-1.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2009 | Pubmed ID: 19234158
Redox modulation protects islets from transplant-related injury.
Diabetes Jul, 2010 | Pubmed ID: 20413509
FoxO1 links hepatic insulin action to endoplasmic reticulum stress.
Endocrinology Aug, 2010 | Pubmed ID: 20501674
Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome.
American journal of physiology. Endocrinology and metabolism May, 2011 | Pubmed ID: 21343540
Hemoglobin A1C Percentage in Nonhuman Primates: A Useful Tool to Monitor Diabetes before and after Porcine Pancreatic Islet Xenotransplantation.
Journal of transplantation , 2011 | Pubmed ID: 21559266
A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice.
Immunologic research Aug, 2011 | Pubmed ID: 21717080
Pig-to-nonhuman primates pancreatic islet xenotransplantation: an overview.
Current diabetes reports Oct, 2011 | Pubmed ID: 21805400
Isolation of human islets for autologous islet transplantation in children and adolescents with chronic pancreatitis.
Journal of transplantation , 2012 | Pubmed ID: 22461976
FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival.
Molecular endocrinology (Baltimore, Md.) Jul, 2012 | Pubmed ID: 22570335
Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model.
Cellular & molecular immunology Nov, 2012 | Pubmed ID: 23042535
Increased yield and improved transplantation outcome of mouse islets with bovine serum albumin.
Journal of transplantation , 2012 | Pubmed ID: 23304445
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering.
Biomaterials Sep, 2013 | Pubmed ID: 23787110
Compromised central tolerance of ICA69 induces multiple organ autoimmunity.
Journal of autoimmunity Sep, 2014 | Pubmed ID: 25088457
Streptozotocin-associated lymphopenia in cynomolgus monkeys.
Islets , 2014 | Pubmed ID: 25322828
Bioengineering mini functional thymic units with EAK16-II/EAKIIH6 self-assembling hydrogel.
Clinical immunology (Orlando, Fla.) Sep, 2015 | Pubmed ID: 25805654
Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2015 | Pubmed ID: 25903472
In vitro exposure of pig neonatal isletlike cell clusters to human blood.
Xenotransplantation Jul-Aug, 2015 | Pubmed ID: 26179209
Endoscopic biopsy of islet transplants in the gastric submucosal space provides evidence of islet graft rejection in diabetic pigs.
Islets Jan, 2016 | Pubmed ID: 26857703
Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes.
Journal of autoimmunity May, 2016 | Pubmed ID: 27173406
Ying Lu*,1,
Shangyou Zou*,1,
Suzanne Bertera*,2,
Rita Bottino2,
David K.C. Cooper3,
Zhengzhao Liu1,
Yi Huang1,
Chengjun Wang1,
Chungu Hong1,
Tian He1,
Hancheng Zhang1,
Qin Huo4,
Hongxing Fu5,
Zhiming Cai1,
Lisha Mou1
1Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen University School of Medicine, Shenzhen University Health Science Center,
2Institute for Cellular Therapeutics, Allegheny-Singer Research Institute,
3Xenotransplantation Program/Department of Surgery, The University of Alabama at Birmingham,
4College of Life Science and Oceanography, Shenzhen University,
5School of Pharmcy, Wenzhou Medical College