Ying Litingtung

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.

Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis.

Cholesterol modification restricts the spread of Shh gradient in the limb bud.

Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia.

Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly.

Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord.

Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice.

Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis.

Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development.

Shh and Gli3 activities are required for timely generation of motor neuron progenitors.

Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus.

Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.