Nadia Carlesso

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome.

Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells.

Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter.

Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways.

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation.

Molecular and functional evidence for activity of murine IL-7 on human lymphocytes.

Delta-like 4 induces notch signaling in macrophages: implications for inflammation.

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis.

Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction.

Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function.

Stem cell regulatory niches and their role in normal and malignant hematopoiesis.

Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function.

Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.

The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs.

Impact of maturational status on the ability of osteoblasts to enhance the hematopoietic function of stem and progenitor cells.

When IFN interferes with cell fate.

Autonomous murine T cell progenitor production in the extra-embryonic yolk sac prior to HSC emergence.

Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.

p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.

Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.

Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity.

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche.

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity.

Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells.

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone.

Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma.

Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88.

S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.

Structural and functional characterization of endothelial microparticles released by cigarette smoke.

Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.