Department of Medicine
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Seroprevalence of H. pylori infection and symptoms of upper gastrointestinal tract disease in two groups of health-care workers.
Digestive diseases and sciences Feb, 2002 | Pubmed ID: 11855543
Heterozygosity for factor V Leiden and G20210A prothrombin genotypes in a patient with mesenteric vein thrombosis.
Digestive diseases and sciences Mar, 2002 | Pubmed ID: 11911349
Deoxycholic acid conjugates are muscarinic cholinergic receptor antagonists.
Pharmacology Aug, 2002 | Pubmed ID: 12119452
Lithocholylcholine, a bile acid/acetylcholine hybrid, is a muscarinic receptor antagonist.
The Journal of pharmacology and experimental therapeutics Oct, 2002 | Pubmed ID: 12235229
Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line.
Biochimica et biophysica acta Oct, 2002 | Pubmed ID: 12379313
Selective interaction of bile acids with muscarinic receptors: a case of molecular mimicry.
European journal of pharmacology Dec, 2002 | Pubmed ID: 12464352
Activation of muscarinic receptor signaling by bile acids: physiological and medical implications.
Digestive diseases and sciences Aug, 2003 | Pubmed ID: 12924634
Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells.
Cancer research Oct, 2003 | Pubmed ID: 14583469
Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R-/- mice.
European journal of pharmacology Jun, 2004 | Pubmed ID: 15189773
Hepatitis C knowledge among primary care residents: is our teaching adequate for the times?
The American journal of gastroenterology Sep, 2004 | Pubmed ID: 15330909
3',5'-Cyclic diguanylic acid (c-di-GMP) inhibits basal and growth factor-stimulated human colon cancer cell proliferation.
Biochemical and biophysical research communications Apr, 2005 | Pubmed ID: 15721270
Cholinergic agonist-induced pepsinogen secretion from murine gastric chief cells is mediated by M1 and M3 muscarinic receptors.
American journal of physiology. Gastrointestinal and liver physiology Sep, 2005 | Pubmed ID: 15933222
A survey of credentialing practices of gastrointestinal endoscopy centers in the United States.
Journal of clinical gastroenterology Jul, 2005 | Pubmed ID: 15942436
Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent.
European journal of pharmacology Jul, 2005 | Pubmed ID: 15964566
Declining gastrointestinal opportunistic infections in HIV-infected persons: a triumph of science and a challenge for our HAARTs and minds.
The American journal of gastroenterology Jul, 2005 | Pubmed ID: 15984965
Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors.
Biochemical pharmacology Oct, 2005 | Pubmed ID: 16139803
Quality assessment of colonoscopic cecal intubation: an analysis of 6 years of continuous practice at a university hospital.
The American journal of gastroenterology Apr, 2006 | Pubmed ID: 16494586
Matrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.
Biochemical pharmacology Apr, 2007 | Pubmed ID: 17222808
Human cecal bile acids: concentration and spectrum.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2007 | Pubmed ID: 17412828
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
Journal of cellular physiology May, 2008 | Pubmed ID: 18064605
Genetic ablation of M3 muscarinic receptors attenuates murine colon epithelial cell proliferation and neoplasia.
Cancer research May, 2008 | Pubmed ID: 18483237
Acetylcholine release by human colon cancer cells mediates autocrine stimulation of cell proliferation.
American journal of physiology. Gastrointestinal and liver physiology Sep, 2008 | Pubmed ID: 18653726
Muscarinic receptors and ligands in cancer.
American journal of physiology. Cell physiology Feb, 2009 | Pubmed ID: 19036940
Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.
Experimental cell research Feb, 2009 | Pubmed ID: 19056378
Acetylcholine-induced activation of M3 muscarinic receptors stimulates robust matrix metalloproteinase gene expression in human colon cancer cells.
American journal of physiology. Gastrointestinal and liver physiology Apr, 2009 | Pubmed ID: 19221016
Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter.
Molecular pharmaceutics Sep-Oct, 2009 | Pubmed ID: 19673539
Gastrointestinal peptides and regulation of gastric acid secretion.
Current opinion in endocrinology, diabetes, and obesity Feb, 2010 | Pubmed ID: 19855274
Scopolamine treatment and muscarinic receptor subtype-3 gene ablation augment azoxymethane-induced murine liver injury.
The Journal of pharmacology and experimental therapeutics Jun, 2010 | Pubmed ID: 20197374
In vivo magnetic resonance imaging to detect biliary excretion of 19F-labeled drug in mice.
Drug metabolism and disposition: the biological fate of chemicals May, 2011 | Pubmed ID: 21270105
Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.
American journal of physiology. Gastrointestinal and liver physiology May, 2011 | Pubmed ID: 21273532
Muscarinic receptor subtype-3 gene ablation and scopolamine butylbromide treatment attenuate small intestinal neoplasia in Apcmin/+ mice.
Carcinogenesis Sep, 2011 | Pubmed ID: 21705482
Bile acids regulate cardiovascular function.
Clinical and translational science Jun, 2011 | Pubmed ID: 21707953
Anatomic classification of the endoscopic appearance of the normal appendiceal orifice: a novel tool for recognition and documentation of cecal intubation.
Clinical anatomy (New York, N.Y.) May, 2012 | Pubmed ID: 21913231
Muscarinic receptor agonists stimulate matrix metalloproteinase 1-dependent invasion of human colon cancer cells.
Biochemical and biophysical research communications Nov, 2011 | Pubmed ID: 22027145
Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteries.
PloS one , 2012 | Pubmed ID: 22359652
Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation.
American journal of physiology. Gastrointestinal and liver physiology May, 2012 | Pubmed ID: 22361730
SlimQuick™ - associated hepatotoxicity in a woman with alpha-1 antitrypsin heterozygosity.
World journal of hepatology Apr, 2012 | Pubmed ID: 22567188
Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.
PloS one , 2012 | Pubmed ID: 23119029
Design and characterization of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile Acid transporter activity.
Pharmaceutical research May, 2013 | Pubmed ID: 23319170
RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer.
Inflammatory bowel diseases May, 2013 | Pubmed ID: 23567782
Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.
BMC cancer Apr, 2013 | Pubmed ID: 23617763
Effects of modulating M3 muscarinic receptor activity on azoxymethane-induced liver injury in mice.
Biochemical pharmacology Jul, 2013 | Pubmed ID: 23707755
Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma.
Mayo Clinic proceedings Nov, 2013 | Pubmed ID: 24100192
The Cdc42/Rac nucleotide exchange factor protein β1Pix (Pak-interacting exchange factor) modulates β-catenin transcriptional activity in colon cancer cells: evidence for direct interaction of β1PIX with β-catenin.
The Journal of biological chemistry Nov, 2013 | Pubmed ID: 24129564
Muscarinic receptor signaling in colon cancer.
Cancers Mar, 2011 | Pubmed ID: 24212649
Phrygian Cap Appearance of a Mouse Gallbladder on Magnetic Resonance Imaging.
Journal of veterinary science & medical diagnosis Mar, 2013 | Pubmed ID: 24371838
The role of matrix metalloproteinases in colorectal cancer.
Cancers Feb, 2014 | Pubmed ID: 24518611
Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia.
Molecular cancer , 2014 | Pubmed ID: 24694019
In vivo performance of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile acid transport.
Molecular pharmaceutics May, 2014 | Pubmed ID: 24708306
Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.
Journal of pharmaceutical sciences Nov, 2014 | Pubmed ID: 25196788
M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.
Free radical biology & medicine Jan, 2015 | Pubmed ID: 25452146
Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium.
Inflammatory bowel diseases Aug, 2015 | Pubmed ID: 25985244
Pharmacokinetics and Tolerability of Intravenous Sildenafil in Two Subjects with Child-Turcotte-Pugh Class C Cirrhosis and Renal Dysfunction.
Digestive diseases and sciences Nov, 2015 | Pubmed ID: 26143343
Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.
Carcinogenesis Oct, 2015 | Pubmed ID: 26210740
Role of the Aryl Hydrocarbon Receptor in Colon Neoplasia.
Cancers Jul, 2015 | Pubmed ID: 26264025
M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice.
Scientific reports Sep, 2015 | Pubmed ID: 26374068
Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells.
Molecular cancer Oct, 2015 | Pubmed ID: 26463716
Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2016 | Pubmed ID: 27173511
Jessica Felton1,
Kunrong Cheng2,
Anan Said2,
Aaron C. Shang2,
Su Xu3,
Diana Vivian4,
Melissa Metry5,
James E. Polli5,
Jean-Pierre Raufman2,6
1Department of Surgery, University of Maryland School of Medicine,
2Department of Medicine, University of Maryland School of Medicine,
3Department of Radiology, University of Maryland School of Medicine,
4, Food and Drug Administration,
5Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy,
6, VA Maryland Health Care System