Laboratory of Cell and Tissue Biology
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RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta.
Nature Apr, 2002 | Pubmed ID: 11961557
Promoter specificity and biological activity of tethered AP-1 dimers.
Molecular and cellular biology Jul, 2002 | Pubmed ID: 12052899
SIAH1 inactivation correlates with tumor progression in hepatocellular carcinomas.
Genes, chromosomes & cancer Mar, 2003 | Pubmed ID: 12557228
Optical cell with a temperature-control unit for a vacuum-ultraviolet circular dichroism spectrophotometer.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry Jan, 2003 | Pubmed ID: 12558036
Suppressed complement activation in human decay accelerating factor transgenic porcine liver cross-circulated with nonhuman primates.
Transplantation Jun, 2003 | Pubmed ID: 12811238
Vacuum-ultraviolet circular dichroism study of saccharides by synchrotron radiation spectrophotometry.
Carbohydrate research Feb, 2004 | Pubmed ID: 15013395
Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer.
Cancer science Apr, 2004 | Pubmed ID: 15072591
Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15073183
Secondary-structure analysis of proteins by vacuum-ultraviolet circular dichroism spectroscopy.
Journal of biochemistry Mar, 2004 | Pubmed ID: 15113839
Severe hyperreninemic hypertension associated with spontaneous renal cholesterol crystal embolization.
Clinical and experimental nephrology Jun, 2004 | Pubmed ID: 15235933
Osteoclasts, mononuclear phagocytes, and c-Fos: new insight into osteoimmunology.
The Keio journal of medicine Jun, 2004 | Pubmed ID: 15247511
Detection of osteoclastic cell-cell fusion through retroviral vector packaging.
Bone Nov, 2004 | Pubmed ID: 15542037
Absence of PERV infection in baboons after transgenic porcine liver perfusion.
The Journal of surgical research Mar, 2005 | Pubmed ID: 15734478
Improved estimation of the secondary structures of proteins by vacuum-ultraviolet circular dichroism spectroscopy.
Journal of biochemistry Jul, 2005 | Pubmed ID: 16046451
[Transcription factors in osteoclast differentiation].
Nihon rinsho. Japanese journal of clinical medicine Sep, 2005 | Pubmed ID: 16164209
Vacuum-ultraviolet circular dichroism analysis of biomolecules.
Chirality May, 2006 | Pubmed ID: 16557527
Resorption of auditory ossicles and hearing loss in mice lacking osteoprotegerin.
Bone Aug, 2006 | Pubmed ID: 16564235
c-Fos suppresses systemic inflammatory response to endotoxin.
International immunology May, 2006 | Pubmed ID: 16569682
Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Apr, 2006 | Pubmed ID: 16598380
Selective metal binding by Vanabin2 from the vanadium-rich ascidian, Ascidia sydneiensis samea.
Biochimica et biophysica acta Jul, 2006 | Pubmed ID: 16631310
[Two autopsy cases of ANCA-associated glomerulonephritis manifested after contrast medium use].
Nihon Jinzo Gakkai shi , 2004 | Pubmed ID: 16773800
[Two cases of classical polyarteritis nodosa associated with MPO-ANCA].
Nihon Jinzo Gakkai shi , 2006 | Pubmed ID: 16780107
Vacuum-ultraviolet electronic circular dichroism of L-alanine in aqueous solution investigated by time-dependent density functional theory.
The journal of physical chemistry. A Aug, 2005 | Pubmed ID: 16834050
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis.
Cell metabolism Aug, 2006 | Pubmed ID: 16890539
Receptor activator of NF-kappa B ligand and osteoprotegerin regulate proinflammatory cytokine production in mice.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2006 | Pubmed ID: 16951341
Murine osteoblasts respond to LPS and IFN-gamma similarly to macrophages.
Journal of bone and mineral metabolism , 2006 | Pubmed ID: 17072737
c-Fos-deficient mice are susceptible to Salmonella enterica serovar Typhimurium infection.
Infection and immunity Mar, 2007 | Pubmed ID: 17178788
Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.
Bone Apr, 2007 | Pubmed ID: 17189721
Secondary-structure analysis of denatured proteins by vacuum-ultraviolet circular dichroism spectroscopy.
Biophysical journal Jun, 2007 | Pubmed ID: 17369421
Induction of DC-STAMP by alternative activation and downstream signaling mechanisms.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jul, 2007 | Pubmed ID: 17402846
NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.
The Journal of biological chemistry Jun, 2007 | Pubmed ID: 17485464
Amyloid protofibril is highly voluminous and compressible.
Biochemistry Sep, 2007 | Pubmed ID: 17715944
Flagella facilitate escape of Salmonella from oncotic macrophages.
Journal of bacteriology Nov, 2007 | Pubmed ID: 17873035
[A survey of Japanese nurses' opinions on nurse anesthetists].
Masui. The Japanese journal of anesthesiology Jan, 2008 | Pubmed ID: 18214013
ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses.
DNA repair Mar, 2008 | Pubmed ID: 18249159
[Assessment of bone quality. Bone remodeling and bone quality].
Clinical calcium Mar, 2008 | Pubmed ID: 18310818
Improved sequence-based prediction of protein secondary structures by combining vacuum-ultraviolet circular dichroism spectroscopy with neural network.
Proteins Oct, 2008 | Pubmed ID: 18395813
Osteoclast-osteoblast communication.
Archives of biochemistry and biophysics May, 2008 | Pubmed ID: 18406338
Low-dose landiolol for hypertension with tachycardia following neurosurgery.
Journal of anesthesia , 2008 | Pubmed ID: 18500624
Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2008 | Pubmed ID: 18552177
Bisphosphonate therapy ameliorates hearing loss in mice lacking osteoprotegerin.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan, 2009 | Pubmed ID: 18715136
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.
Immunity Sep, 2008 | Pubmed ID: 18799150
Signaling flux redistribution at toll-like receptor pathway junctions.
PloS one , 2008 | Pubmed ID: 18927610
[Pharmaceutical services for patients receiving AC chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy Feb, 2009 | Pubmed ID: 19223738
Vacuum-ultraviolet circular dichroism analysis of glycosaminoglycans by synchrotron-radiation spectroscopy.
Bioscience, biotechnology, and biochemistry Mar, 2009 | Pubmed ID: 19270385
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis.
The Journal of biological chemistry May, 2009 | Pubmed ID: 19299512
A novel vanadium reductase, Vanabin2, forms a possible cascade involved in electron transfer.
Biochimica et biophysica acta Apr, 2009 | Pubmed ID: 19336037
Cross-talk among bone cells.
Current opinion in nephrology and hypertension Jul, 2009 | Pubmed ID: 19395964
Comprehensive secondary-structure analysis of disulfide variants of lysozyme by synchrotron-radiation vacuum-ultraviolet circular dichroism.
Proteins Oct, 2009 | Pubmed ID: 19434752
Characterization of vanadium-binding sites of the vanadium-binding protein Vanabin2 by site-directed mutagenesis.
Biochimica et biophysica acta Oct, 2009 | Pubmed ID: 19501132
Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Dec, 2009 | Pubmed ID: 19558315
The mechanism of osteoclast differentiation induced by IL-1.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19587010
IL-27 abrogates receptor activator of NF-kappa B ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19620301
Membrane-induced conformational change of alpha1-acid glycoprotein characterized by vacuum-ultraviolet circular dichroism spectroscopy.
Biochemistry Sep, 2009 | Pubmed ID: 19702310
Eph and ephrin interactions in bone.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 19950019
Fos proteins suppress dextran sulfate sodium-induced colitis through inhibition of NF-kappaB.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2010 | Pubmed ID: 20018614
Differences in the molecular structure of beta(2)-microglobulin between two morphologically different amyloid fibrils.
Biochemistry Feb, 2010 | Pubmed ID: 20028123
[Analysis of a case of oxaliplatin - induced persistence sensory neuropathy].
Gan to kagaku ryoho. Cancer & chemotherapy Mar, 2010 | Pubmed ID: 20332703
[Preventing dermatopathy of patients receiving cancer chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy Sep, 2010 | Pubmed ID: 20841938
EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation.
Bone Mar, 2011 | Pubmed ID: 21056708
Spectroscopic Characterization of Intermolecular Interaction of Amyloid β Promoted on GM1 Micelles.
International journal of Alzheimer's disease Dec, 2010 | Pubmed ID: 21318130
Impaired vibration of auditory ossicles in osteopetrotic mice.
The American journal of pathology Mar, 2011 | Pubmed ID: 21356377
Experimental and theoretical studies of vacuum-ultraviolet electronic circular dichroism of hydroxy acids in aqueous solution.
Chirality , 2011 | Pubmed ID: 21538575
A CD46 transgenic mouse model for studying the histopathology of arthritis caused by subcutaneous infection with Streptococcus dysgalactiae subspecies equisimilis.
Journal of medical microbiology Dec, 2011 | Pubmed ID: 21852528
Secondary-structure analysis of alcohol-denatured proteins by vacuum-ultraviolet circular dichroism spectroscopy.
Proteins Jan, 2012 | Pubmed ID: 22076921
Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study.
Critical care (London, England) Feb, 2012 | Pubmed ID: 22373120
[Osteocytic osteolysis : measurements of the volume of osteocytic lacunae].
Clinical calcium May, 2012 | Pubmed ID: 22549192
Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion.
The Journal of cell biology May, 2012 | Pubmed ID: 22584907
Cot kinase promotes Ca2+ oscillation/calcineurin-independent osteoclastogenesis by stabilizing NFATc1 protein.
Molecular and cellular biology Jul, 2012 | Pubmed ID: 22615493
Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseases.
Cell adhesion & migration Mar-Apr, 2012 | Pubmed ID: 22660185
Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts.
Experimental hematology Nov, 2012 | Pubmed ID: 22771497
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Arthritis and rheumatism Nov, 2012 | Pubmed ID: 22833446
RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.
Cancer research Oct, 2012 | Pubmed ID: 22865450
A sensitive method based on fluorescence-detected circular dichroism for protein local structure analysis.
Analytical biochemistry Nov, 2012 | Pubmed ID: 22940648
Vacuum-ultraviolet electronic circular dichroism study of methyl α-D-glucopyranoside in aqueous solution by time-dependent density functional theory.
The journal of physical chemistry. A Oct, 2012 | Pubmed ID: 22950837
[Regulation of bone metabolism by Eph-ephrin family members].
Clinical calcium Nov, 2012 | Pubmed ID: 23103810
EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Apr, 2013 | Pubmed ID: 23165754
[Osteoimmunologic regulation of aging].
Clinical calcium Jan, 2013 | Pubmed ID: 23268303
Regulation of osteoclasts by membrane-derived lipid mediators.
Cellular and molecular life sciences : CMLS Sep, 2013 | Pubmed ID: 23296124
Gefitinib, but not erlotinib, is a possible inducer of Fra-1-mediated interstitial lung disease.
The Keio journal of medicine , 2012 | Pubmed ID: 23324306
Molecular mechanisms of triggering, amplifying and targeting RANK signaling in osteoclasts.
World journal of orthopedics Nov, 2012 | Pubmed ID: 23330071
Circular-dichroism and synchrotron-radiation circular-dichroism spectroscopy as tools to monitor protein structure in a lipid environment.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23404276
Roussoellols A and B, tetracyclic fusicoccanes from Roussoella hysterioides.
Journal of natural products Jun, 2013 | Pubmed ID: 23692046
Possible role of IRTKS in Tks5-driven osteoclast fusion.
Communicative & integrative biology Sep, 2012 | Pubmed ID: 23739834
Talbot-defocus multiscan tomography using the synchrotron X-ray microscope to study the lacuno-canalicular network in mouse bone.
Biomedical optics express Jun, 2013 | Pubmed ID: 23761853
Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.
Cancer research Aug, 2013 | Pubmed ID: 23811942
[Updates on rickets and osteomalacia: mechanism and regulation of bone mineralization].
Clinical calcium Oct, 2013 | Pubmed ID: 24076644
[Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan , 2014 | Pubmed ID: 24492229
Characterization of intermolecular structure of β(2)-microglobulin core fragments in amyloid fibrils by vacuum-ultraviolet circular dichroism spectroscopy and circular dichroism theory.
The journal of physical chemistry. B Mar, 2014 | Pubmed ID: 24512563
Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1.
Experimental hematology Jun, 2014 | Pubmed ID: 24530466
Linezolid minimum inhibitory concentration (MIC) creep in methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates at a single Japanese center.
Biological & pharmaceutical bulletin , 2014 | Pubmed ID: 24694615
Overexpression, purification, and characterization of Paenibacillus cell surface-expressed chitinase ChiW with two catalytic domains.
Bioscience, biotechnology, and biochemistry , 2014 | Pubmed ID: 25036959
[Glucocorticoid and Bone. Osteocytic osteolysis : potential modulation by glucocorticoids].
Clinical calcium Sep, 2014 | Pubmed ID: 25177006
IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress.
Cancer research Nov, 2014 | Pubmed ID: 25273088
An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A.
FEBS open bio , 2014 | Pubmed ID: 25379380
Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation.
The Journal of experimental medicine Nov, 2014 | Pubmed ID: 25385757
Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research May, 2015 | Pubmed ID: 25431176
The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.
The American journal of pathology Feb, 2015 | Pubmed ID: 25453723
A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts.
PloS one , 2015 | Pubmed ID: 25617756
A case of primary adenocarcinoma of the third portion of the duodenum resected by laparoscopic and endoscopic cooperating surgery.
International journal of surgery case reports , 2015 | Pubmed ID: 25723745
Effects of Comb Tooth Cap Medicinal Mushroom, Hericium ramosum (Higher Basidiomycetes) Mycelia on DPPH Radical Scavenging Activity and Nerve Growth Factor Synthesis.
International journal of medicinal mushrooms , 2015 | Pubmed ID: 25954959
EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.
Stem cells (Dayton, Ohio) Sep, 2015 | Pubmed ID: 26033476
Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication.
Brain research Oct, 2015 | Pubmed ID: 26254727
Vacuum-Ultraviolet Circular Dichroism Spectra of Escherichia coli Dihydrofolate Reductase and Its Mutants: Contributions of Phenylalanine and Tyrosine Side Chains and Exciton Coupling of Two Tryptophan Side Chains.
The journal of physical chemistry. B Oct, 2015 | Pubmed ID: 26407224
[Bone Cell Biology Assessed by Microscopic Approach. Regulation of bone mineralization through the osteocyte lacuno-canalicular network].
Clinical calcium Oct, 2015 | Pubmed ID: 26412724
Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus.
Development (Cambridge, England) Nov, 2015 | Pubmed ID: 26428006
Isotope effect on the circular dichroism spectrum of methyl α-D-glucopyranoside in aqueous solution.
Scientific reports Dec, 2015 | Pubmed ID: 26658851
Osteocyte-directed bone demineralization along canaliculi.
Bone Mar, 2016 | Pubmed ID: 26709236
Osteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial Invasion.
PloS one , 2016 | Pubmed ID: 26751951
Conformation of membrane-bound proteins revealed by vacuum-ultraviolet circular-dichroism and linear-dichroism spectroscopy.
Proteins Mar, 2016 | Pubmed ID: 26756612
Flesh-eating Streptococcus pyogenes triggers the expression of receptor activator of nuclear factor-κB ligand.
Cellular microbiology Oct, 2016 | Pubmed ID: 26894505
Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice.
Journal of the neurological sciences Mar, 2016 | Pubmed ID: 26944163
Secondary Structure Prediction of Protein Constructs Using Random Incremental Truncation and Vacuum-Ultraviolet CD Spectroscopy.
PloS one , 2016 | Pubmed ID: 27273007
Usefulness of transanal tube placement for prevention of anastomotic leakage following laparoscopic low anterior resection.
Asian journal of endoscopic surgery Feb, 2017 | Pubmed ID: 27456989
DNA damage response induces structural alterations in histone H3-H4.
Journal of radiation research Sep, 2016 | Pubmed ID: 27672100
Simvastatin-induced apoptosis in osteosarcoma cells: a key role of RhoA-AMPK-p38 MAPK signaling in antitumor activity.
Molecular cancer therapeutics Oct, 2016 | Pubmed ID: 27799356
The Association of Fever with Total Mechanical Ventilation Time in Critically Ill Patients.
Journal of Korean medical science Dec, 2016 | Pubmed ID: 27822946