Cystic Fibrosis Regional Center (CFC)
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MAP kinases and NF-kappaB collaborate to induce ICAM-1 gene expression in the early phase of adenovirus infection.
Virology Mar, 2003 | Pubmed ID: 12667793
The GCC repeat length in the 5'UTR of MRP1 gene is polymorphic: a functional characterization of its relevance for cystic fibrosis.
BMC medical genetics Feb, 2006 | Pubmed ID: 16464259
Interaction of adenovirus type 5 fiber with the coxsackievirus and adenovirus receptor activates inflammatory response in human respiratory cells.
Journal of virology Nov, 2006 | Pubmed ID: 16956941
Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells.
Biochemical and biophysical research communications Dec, 2006 | Pubmed ID: 17045242
Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells.
Antimicrobial agents and chemotherapy Mar, 2007 | Pubmed ID: 17210769
TG15 T5 allele in clinically discordant monozygotic twins with cystic fibrosis.
American journal of medical genetics. Part A Aug, 2007 | Pubmed ID: 17632788
Effects of azithromycin on glutathione S-transferases in cystic fibrosis airway cells.
American journal of respiratory cell and molecular biology Aug, 2009 | Pubmed ID: 19097986
CFTR mutation in an Arab patient: clinical and functional features of 875+1G-->A/875+1G-->A genotype.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jul, 2009 | Pubmed ID: 19481507
Protein Tyrosine Phosphatase Gamma (PTPgamma) is a Novel Leukocyte Marker Highly Expressed by CD34 Precursors.
Biomarker insights May, 2007 | Pubmed ID: 19662205
Editorial: The role of macrophages and their scavenger receptors in cystic fibrosis.
Journal of leukocyte biology Sep, 2009 | Pubmed ID: 19720614
Whole blood fatty acid analysis with micromethod in cystic fibrosis and pulmonary disease.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society May, 2010 | Pubmed ID: 20338832
An interactive computer program can effectively educate potential users of cystic fibrosis carrier tests.
American journal of medical genetics. Part A Apr, 2011 | Pubmed ID: 21416590
Impact of polymorphism of Multidrug Resistance-associated Protein 1 (ABCC1) gene on the severity of cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jul, 2011 | Pubmed ID: 21435954
Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.
PloS one , 2011 | Pubmed ID: 21811577
MudPIT analysis of released proteins in Pseudomonas aeruginosa laboratory and clinical strains in relation to pro-inflammatory effects.
Integrative biology : quantitative biosciences from nano to macro Mar, 2012 | Pubmed ID: 22298109
Contribution by polymorphonucleate granulocytes to elevated gamma-glutamyltransferase in cystic fibrosis sputum.
PloS one , 2012 | Pubmed ID: 22496859
Influence of perfusate temperature on nasal potential difference.
The European respiratory journal Aug, 2013 | Pubmed ID: 23100510
Impaired CFTR function in mild cystic fibrosis associated with the S977F/T5TG12complex allele in trans with F508del mutation.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Dec, 2013 | Pubmed ID: 23361109
γ-Glutamyltransferase catabolism of S-nitrosoglutathione modulates IL-8 expression in cystic fibrosis bronchial epithelial cells.
Free radical biology & medicine Dec, 2013 | Pubmed ID: 23820266
Nasal potential difference measurements in diagnosis of cystic fibrosis: an international survey.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jan, 2014 | Pubmed ID: 24022019
Glutathione inhalation treatments in cystic fibrosis: the interference of airway γ-glutamyltransferase.
American journal of respiratory and critical care medicine Jan, 2014 | Pubmed ID: 24428657
Challenging the diagnosis of cystic fibrosis in a patient carrying the 186-8T/C allelic variant in the CF transmembrane conductance regulator gene.
BMC pulmonary medicine Mar, 2014 | Pubmed ID: 24621136
Detection of CFTR protein in human leukocytes by flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Jul, 2014 | Pubmed ID: 24623386
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial.
The Lancet. Respiratory medicine Jul, 2014 | Pubmed ID: 24836205
Electrophysiological evaluation of cystic fibrosis conductance transmembrane regulator (CFTR) expression in human monocytes.
Biochimica et biophysica acta Oct, 2014 | Pubmed ID: 25046381
Impact of MIF gene promoter polymorphism on F508del cystic fibrosis patients.
PloS one , 2014 | Pubmed ID: 25503271
In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin.
Journal of translational medicine Aug, 2015 | Pubmed ID: 26239109
Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency.
American journal of respiratory and critical care medicine May, 2016 | Pubmed ID: 26694899
HLA-G expression and regulation during Pseudomonas aeruginosa infection in cystic fibrosis patients.
Future microbiology , 2016 | Pubmed ID: 26934639
Biogenic selenium nanoparticles: characterization, antimicrobial activity and effects on human dendritic cells and fibroblasts.
Microbial biotechnology Nov, 2016 | Pubmed ID: 27319803
Genotypic and phenotypic relatedness of Pseudomonas aeruginosa isolates among the major cystic fibrosis patient cohort in Italy.
BMC microbiology Jul, 2016 | Pubmed ID: 27400750
Nasal potential difference outcomes support diagnostic decisions in cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Sep, 2016 | Pubmed ID: 27423539
In vivo monitoring of lung inflammation in CFTR-deficient mice.
Journal of translational medicine Jul, 2016 | Pubmed ID: 27468800
Whole-gene CFTR sequencing combined with digital RT-PCR improves genetic diagnosis of cystic fibrosis.
Journal of human genetics Dec, 2016 | Pubmed ID: 27488443
Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium.
Frontiers in immunology , 2016 | Pubmed ID: 27895643
Ratiometric sweat secretion optical test in cystic fibrosis, carriers and healthy subjects.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Mar, 2018 | Pubmed ID: 29292091
Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice.
Virulence , 2018 | Pubmed ID: 29938577
When and how ruling out cystic fibrosis in adult patients with bronchiectasis.
Multidisciplinary respiratory medicine , 2018 | Pubmed ID: 30151190
Gabriella Bergamini*,1,
Fabio Stellari*,2,
Angela Sandri*,3,
Maria M. Lleo3,
Gaetano Donofrio4,
Francesca Ruscitti5,2,
Federico Boschi6,
Andrea Sbarbati7,
Gino Villetti2,
Paola Melotti8,
Claudio Sorio1
1Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona,
2Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A.,
3Department of Diagnostic and Public Health, Microbiology Division, University of Verona,
4Dipartimento di Scienze Medico-Veterinarie, University of Parma,
5Department of Biomedical Biotechnological and Translational Sciences, University of Parma,
6Department of Computer Science, University of Verona,
7Department of Neurological, Biomedical and Movement Sciences, University of Verona,
8Cystic Fibrosis Regional Center (CFC), AOUI Verona
George M. Solomon1,
Inez Bronsveld2,
Kathryn Hayes3,
Michael Wilschanski4,
Paola Melotti5,
Steven M. Rowe1,
Isabelle Sermet-Gaudelus6,7
1Department of Medicine and the Gregory Fleming James Cystic Fibrosis Center, University of Alabama at Birmingham,
2Department of Pulmonology and Tuberculosis, University Medical Center Utrecht,
3Center for Experimental Medicine, Queens University, Northern Ireland,
4, Hadassah Hebrew University Medical Center, Jerusalem,
5Centro Fibrosi Cistica, Azienda Ospedaliera Universitaria Integrata,
6Service de Pneumologie et Allergologie Pédiatriques and Center de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades,
7INSERM U 1151, Institut Necker Enfants Malades