Paul C. Letourneau

Temporal regulation of neuropilin-1 expression and sensitivity to semaphorin 3A in NGF- and NT3-responsive chick sensory neurons.

Transient PKA activity is required for initiation but not maintenance of BDNF-mediated protection from nitric oxide-induced growth-cone collapse.

Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse.

Nerve growth factor and semaphorin 3A signaling pathways interact in regulating sensory neuronal growth cone motility.

Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility.

Growth cones integrate signaling from multiple guidance cues.

Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons.

Regulation of growth cone actin filaments by guidance cues.

p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity.

Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide.

Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.

Modifier of cell adhesion regulates N-cadherin-mediated cell-cell adhesion and neurite outgrowth.

Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factor.

Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility.

Changes within maturing neurons limit axonal regeneration in the developing spinal cord.

L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord.

Protein synthesis in distal axons is not required for axon growth in the embryonic spinal cord.

Protein synthesis in distal axons is not required for growth cone responses to guidance cues.

Actin in axons: stable scaffolds and dynamic filaments.

Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1.

Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors.

Repulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins.