Yu-Ju Chen

Methods for detection and characterization of protein S-nitrosylation.

Structural characterization of Escherichia coli sialic acid synthase.

Synthesis of alpha-(2-->5)Neu5Gc oligomers.

Mechanistic aspects of CoII(HAPP)(TFA)2 in DNA bulge-specific recognition.

Production of high-quality particulate methane monooxygenase in high yields from Methylococcus capsulatus (bath) with a hollow-fiber membrane bioreactor.

Purification, tandem mass characterization, and inhibition studies of oxidosqualene-lanosterol cyclase enzyme from bovine liver.

Specific recognition of DNA bulge structure by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Identification of tumor-associated plasma biomarkers using proteomic techniques: from mouse to human.

Quantitative proteomic analysis of metabolic regulation by copper ions in Methylococcus capsulatus (Bath).

Nuclear efflux of heterogeneous nuclear ribonucleoprotein C1/C2 in apoptotic cells: a novel nuclear export dependent on Rho-associated kinase activation.

Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolases.

Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry.

Structural characterization of sialic acid synthase by electrospray mass spectrometry--a tetrameric enzyme composed of dimeric dimers.

Parallel minisequencing followed by multiplex matrix-assisted laser desorption/ionization mass spectrometry assay for beta-thalassemia mutations.

Molecular identification of canine podocalyxin-like protein 1 as a renal tubulogenic regulator.

Carbohydrate-encapsulated gold nanoparticles for rapid target-protein identification and binding-epitope mapping.

Nanoprobe-based affinity mass spectrometry for selected protein profiling in human plasma.

The inhibition of osteogenesis with human bone marrow mesenchymal stem cells by CdSe/ZnS quantum dot labels.

Determination of SMN1/SMN2 gene dosage by a quantitative genotyping platform combining capillary electrophoresis and MALDI-TOF mass spectrometry.

The internalized CdSe/ZnS quantum dots impair the chondrogenesis of bone marrow mesenchymal stem cells.

Site-specific protein modification through Cu(I)-catalyzed 1,2,3-triazole formation and its implementation in protein microarray fabrication.

Multi-Q: a fully automated tool for multiplexed protein quantitation.

Quantitative proteomic and genomic profiling reveals metastasis-related protein expression patterns in gastric cancer cells.

Evaluation of serum amyloid A as a biomarker for gastric cancer.

Ethylene glycol-protected magnetic nanoparticles for a multiplexed immunoassay in human plasma.

Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.

Targeted protein quantitation and profiling using PVDF affinity probe and MALDI-TOF MS.

Improved analysis of membrane protein by PVDF-aided, matrix-assisted laser desorption/ionization mass spectrometry.

Genetic nanomedicine and tissue engineering.

Globotriose-functionalized gold nanoparticles as multivalent probes for Shiga-like toxin.

A multiplexed quantitative strategy for membrane proteomics: opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease.

Multiplexed immunoassay: quantitation and profiling of serum biomarkers using magnetic nanoprobes and MALDI-TOF MS.

Nitric oxide physiological responses and delivery mechanisms probed by water-soluble Roussin's red ester and {Fe(NO)2}10 DNIC.

Immobilized metal affinity chromatography revisited: pH/acid control toward high selectivity in phosphoproteomics.

Nanomaterial based affinity matrix-assisted laser desorption/ionization mass spectrometry for biomolecules and pathogenic bacteria.

Clinical value of application of cerebral oximetry in total replacement of the aortic arch and concomitant vessels.

Priming with rocuronium to accelerate the onset time of cisatracurium during intubation.

Taiwanese medical and nursing student interest levels in and attitudes towards geriatrics.

Risk factors of vomiting among females on patient-controlled epidural analgesia.

Determination of thioglycolic acid in hair-waving products by disposable electrochemical sensor coupled with high-performance liquid chromatography.

Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.

MaXIC-Q Web: a fully automated web service using statistical and computational methods for protein quantitation based on stable isotope labeling and LC-MS.

Role for alpha-L-fucosidase in the control of Helicobacter pylori-infected gastric cancer cells.

IDEAL-Q, an automated tool for label-free quantitation analysis using an efficient peptide alignment approach and spectral data validation.

Fabrication of oriented antibody-conjugated magnetic nanoprobes and their immunoaffinity application.

Temporal proteomics profiling of lipid rafts in CCR6-activated T cells reveals the integration of actin cytoskeleton dynamics.

Identification of in vivo phosphorylation sites of lens proteins from porcine eye lenses by a gel-free phosphoproteomics approach.

The Asia Oceania Human Proteome Organisation Membrane Proteomics Initiative. Preparation and characterisation of the carbonate-washed membrane standard.

Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry.

Dihydrobenzoic acid modified nanoparticle as a MALDI-TOF MS matrix for soft ionization and structure determination of small molecules with diverse structures.

An informatics-assisted label-free quantitation strategy that depicts phosphoproteomic profiles in lung cancer cell invasion.

S-alkylating labeling strategy for site-specific identification of the s-nitrosoproteome.

Genetic diversity and C2-like subgenogroup strains of enterovirus 71, Taiwan, 2008.

Proteomic profiles of bronchoalveolar lavage fluid from patients with ventilator-associated pneumonia by gel-assisted digestion and 2-D-LC/MS/MS.

An informatics-assisted label-free approach for personalized tissue membrane proteomics: case study on colorectal cancer.

Identification of SEC61β and its autoantibody as biomarkers for colorectal cancer.

Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses.

Healthy behaviors and onset of functional disability in older adults: results of a national longitudinal study.

Surface marker epithelial cell adhesion molecule and E-cadherin facilitate the identification and selection of induced pluripotent stem cells.

Task-irrelevant angry faces capture attention in visual search while modulated by resources.

Nanoprobe-based immobilized metal affinity chromatography for sensitive and complementary enrichment of multiply phosphorylated peptides.

Phosphoproteomics identifies oncogenic Ras signaling targets and their involvement in lung adenocarcinomas.

Nanoparticle-assisted MALDI-TOF MS combined with seed-layer surface preparation for quantification of small molecules.

Psychophysiological determinants of repeated ventilator weaning failure: an explanatory model.

Interplay between SIN3A and STAT3 mediates chromatin conformational changes and GFAP expression during cellular differentiation.

SNOSite: exploiting maximal dependence decomposition to identify cysteine S-nitrosylation with substrate site specificity.

In-depth identification of pathways related to cisplatin-induced hepatotoxicity through an integrative method based on an informatics-assisted label-free protein quantitation and microarray gene expression approach.

Iron oxide nanomatrix facilitating metal ionization in matrix-assisted laser desorption/ionization mass spectrometry.

Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry.

Phosphoproteomic analysis of human mesenchymal stromal cells during osteogenic differentiation.

[A study of work stress and professional commitment in outpatient department nurses].

dbSNO: a database of cysteine S-nitrosylation.

Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair.

[Improving comprehensiveness of information given to pediatric cardiac surgery patients prior to surgery].

Complementary Fe(3+)- and Ti(4+)-immobilized metal ion affinity chromatography for purification of acidic and basic phosphopeptides.

Phosphoproteomic analysis of Rhodopseudomonas palustris reveals the role of pyruvate phosphate dikinase phosphorylation in lipid production.

Determinants of emergency medical utilization among the elderly population in Taiwan: a national longitudinal cohort study.

DbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications.

A chemically functionalized magnetic nanoplatform for rapid and specific biomolecular recognition and separation.

Decoding the disease-associated proteins encoded in the human chromosome 4.

An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice.

Androgen modulates cardiac fibrosis contributing to gender differences on heart failure.

Spectrum-based method to generate good decoy libraries for spectral library searching in peptide identifications.

Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development.

Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy.

BAD-lectins: boronic acid-decorated lectins with enhanced binding affinity for the selective enrichment of glycoproteins.

Quantitative proteomic analysis of human lung tumor xenografts treated with the ectopic ATP synthase inhibitor citreoviridin.

Phylogenetic analysis and development of an immunofluorescence assay for untypeable strains of coxsackievirus B3.

Identification of downstream components of ubiquitin-conjugating enzyme PHOSPHATE2 by quantitative membrane proteomics in Arabidopsis roots.

Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions.

Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs.

Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the human protein atlas.

Sequential phosphoproteomic enrichment through complementary metal-directed immobilized metal ion affinity chromatography.

Global analysis of cdc14 dephosphorylation sites reveals essential regulatory role in mitosis and cytokinesis.

Interaction modes and approaches to glycopeptide and glycoprotein enrichment.

Quantitative proteomics analysis highlights the role of redox hemostasis and energy metabolism in human embryonic stem cell differentiation to neural cells.

HSP70 colocalizes with PLK1 at the centrosome and disturbs spindle dynamics in cells arrested in mitosis by arsenic trioxide.

Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model.

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.

Phosphoproteomic analyses reveal that galectin-1 augments the dynamics of B-cell receptor signaling.

Sequential one-pot enzymatic synthesis of oligo-N-acetyllactosamine and its multi-sialylated extensions.

RegPhos 2.0: an updated resource to explore protein kinase-substrate phosphorylation networks in mammals.

dbGSH: a database of S-glutathionylation.

Chromosome-centric Human Proteome Project (C-HPP): Chromosome 12.

Decoding the s-nitrosoproteomic atlas in individualized human colorectal cancer tissues using a label-free quantitation strategy.

The incidence of Japanese encephalitis in Taiwan--a population-based study.

Incorporating amino acids composition and functional domains for identifying bacterial toxin proteins.

An intelligent system for identifying acetylated lysine on histones and nonhistone proteins.

Distinct subpopulations of head and neck cancer cells with different levels of intracellular reactive oxygen species exhibit diverse stemness, proliferation, and chemosensitivity.

dbSNO 2.0: a resource for exploring structural environment, functional and disease association and regulatory network of protein S-nitrosylation.

Characterization and identification of protein O-GlcNAcylation sites with substrate specificity.

Glutathionylspermidine in the modification of protein SH groups: the enzymology and its application to study protein glutathionylation.

MAGIC: an automated N-linked glycoprotein identification tool using a Y1-ion pattern matching algorithm and in silico MS² approach.

Growth changes in infants born of adolescent mothers: Results of a national cohort study in Taiwan.

Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics.

Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.

GSHSite: exploiting an iteratively statistical method to identify s-glutathionylation sites with substrate specificity.

DcR3 suppresses influenza virus-induced macrophage activation and attenuates pulmonary inflammation and lethality.

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition.

Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project.

Qualification and Verification of Serological Biomarker Candidates for Lung Adenocarcinoma by Targeted Mass Spectrometry.

Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation.

Imaging Endogenous Bilirubins with Two-Photon Fluorescence of Bilirubin Dimers.

Mining Missing Membrane Proteins by High-pH Reverse-Phase StageTip Fractionation and Multiple Reaction Monitoring Mass Spectrometry.

The Influence of Phase Separation on Bioactivity of Spray Pyrolyzed Bioactive Glass.

Monodispersity of magnetic immuno-nanoprobes enhances the detection sensitivity of low abundance biomarkers in one drop of serum.

Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC.

Adherence to self-care behavior and glycemic effects using structured education.

Informatics View on the Challenges of Identifying Missing Proteins from Shotgun Proteomics.

Rapid High-pH Reverse Phase StageTip for Sensitive Small-Scale Membrane Proteomic Profiling.

The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42.

Recent Development of Mass Spectrometric Technologies in Asia and Oceania.

A photo-cleavable biotin affinity tag for the facile release of a photo-crosslinked carbohydrate-binding protein.

Comparison of Different Models of Structured Self-Monitoring of Blood Glucose in Type 2 Diabetes.

Thyroid Storm and Incidental Anterior Mediastinal Teratoma: Coincidence or Correlation?

Untargeted, spectral library-free analysis of data-independent acquisition proteomics data generated using Orbitrap mass spectrometers.

The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells.

Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells.

Contest experience and body size affect different types of contest decisions.

Functionalized HgTe nanoparticles promote laser-induced solid phase ionization/dissociation for comprehensive glycan sequencing.

Associations among integrated psychoneuroimmunological factors and metabolic syndrome.

Chemical Inhibition of Human Thymidylate Kinase and Structural Insights into the Phosphate Binding Loop and Ligand-Induced Degradation.

Atomic force microscopy characterization of kinase-mediated phosphorylation of a peptide monolayer.

K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.

Identification of Potential Plasma Biomarkers for Nonalcoholic Fatty Liver Disease by Integrating Transcriptomics and Proteomics in Laying Hens.

Phosphoproteomics Reveals HMGA1, a CK2 Substrate, as a Drug-Resistant Target in Non-Small Cell Lung Cancer.

One-Pot Two-Nanoprobe Assay Uncovers Targeted Glycoprotein Biosignature.

Stockpile Model of Personal Protective Equipment in Taiwan.

Proteome analysis of human embryonic stem cells organelles.

Correction: Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.

Exploring the expression bar code of SAA variants for gastric cancer detection.

Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver.

ER-plasma membrane junctions: Why and how do we study them?

RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P2.

Data for whole and mitochondrial proteome of human embryonic stem cells.

UV-activated multilayer nanomatrix provides one-step tunable carbohydrate structural characterization in MALDI-MS.

Absolute Phosphorylation Stoichiometry Analysis by Motif-Targeting Quantitative Mass Spectrometry.