Department of Neurological Surgery,
Feinberg School of Medicine,
Department of Neurological Surgery, Feinberg School of Medicine
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Epitope-specific antibody-induced cleavage of angiotensin-converting enzyme from the cell surface.
The Biochemical journal Mar, 2002 | Pubmed ID: 11879185
GABA alpha6 receptors mediate midazolam-induced anxiolysis.
Journal of clinical anesthesia May, 2002 | Pubmed ID: 12031754
G alpha 13-mediated transformation and apoptosis are permissively dependent on basal ERK activity.
American journal of physiology. Cell physiology Oct, 2003 | Pubmed ID: 12736137
Epitope-dependent blocking of the angiotensin-converting enzyme dimerization by monoclonal antibodies to the N-terminal domain of ACE: possible link of ACE dimerization and shedding from the cell surface.
Biochemistry Jun, 2003 | Pubmed ID: 12795591
Angiotensin-converting enzyme (CD143) is abundantly expressed by dendritic cells and discriminates human monocyte-derived dendritic cells from acute myeloid leukemia-derived dendritic cells.
Experimental hematology Dec, 2003 | Pubmed ID: 14662338
Selective rat lung endothelial targeting with a new set of monoclonal antibodies to angiotensin I-converting enzyme.
Pulmonary pharmacology & therapeutics , 2005 | Pubmed ID: 15777608
Propofol attenuates lung endothelial injury induced by ischemia-reperfusion and oxidative stress.
Anesthesia and analgesia Apr, 2005 | Pubmed ID: 15781500
Monoclonal antibodies 1B3 and 5C8 as probes for monitoring the integrity of the C-terminal end of soluble angiotensin-converting enzyme.
Hybridoma (2005) Feb, 2005 | Pubmed ID: 15785205
Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies.
Journal of proteome research Mar-Apr, 2005 | Pubmed ID: 15822901
Detection of mutated angiotensin I-converting enzyme by serum/plasma analysis using a pair of monoclonal antibodies.
Clinical chemistry Jun, 2005 | Pubmed ID: 15914791
Testicular isoform of angiotensin I-converting enzyme (ACE, CD143) on the surface of human spermatozoa: revelation and quantification using monoclonal antibodies.
American journal of reproductive immunology (New York, N.Y. : 1989) Jan, 2006 | Pubmed ID: 16364013
Inhibitory antibodies to human angiotensin-converting enzyme: fine epitope mapping and mechanism of action.
Biochemistry Apr, 2006 | Pubmed ID: 16605251
Monoclonal Antibodies 1G12 and 6A12 to the N-domain of human angiotensin-converting enzyme: fine epitope mapping and antibody-based detection of ACE inhibitors in human blood.
Journal of proteome research Apr, 2007 | Pubmed ID: 17326675
Fine epitope mapping of monoclonal antibody 5F1 reveals anticatalytic activity toward the N domain of human angiotensin-converting enzyme.
Biochemistry Aug, 2007 | Pubmed ID: 17630779
Propofol attenuates endotoxin-induced endothelial cell injury, angiotensin-converting enzyme shedding, and lung edema.
Anesthesia and analgesia Nov, 2007 | Pubmed ID: 17959967
Mapping of conformational mAb epitopes to the C domain of human angiotensin I-converting enzyme.
Journal of proteome research Aug, 2008 | Pubmed ID: 18576678
Simultaneous determination of ACE activity with 2 substrates provides information on the status of somatic ACE and allows detection of inhibitors in human blood.
Journal of cardiovascular pharmacology Jul, 2008 | Pubmed ID: 18645413
Genetic modification of mesenchymal stem cells to express a single-chain antibody against EGFRvIII on the cell surface.
Journal of tissue engineering and regenerative medicine Jun, 2010 | Pubmed ID: 19937911
Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma.
PloS one Mar, 2010 | Pubmed ID: 20305783
Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.
Microvascular research Sep, 2010 | Pubmed ID: 20430040
Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model.
Molecular therapy : the journal of the American Society of Gene Therapy Oct, 2010 | Pubmed ID: 20588259
Conformational fingerprinting of the angiotensin I-converting enzyme (ACE). 1. Application in sarcoidosis.
Journal of proteome research Nov, 2010 | Pubmed ID: 20873814
Cloning and characterization of a single-chain fragment of monoclonal antibody to ACE suitable for lung endothelial targeting.
Microvascular research Dec, 2010 | Pubmed ID: 20888351
The expression of BST2 in human and experimental mouse brain tumors.
Experimental and molecular pathology Aug, 2011 | Pubmed ID: 21565182
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2011 | Pubmed ID: 21629227
Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts.
Cancer letters Nov, 2011 | Pubmed ID: 21802840
Functional single-cell hybridoma screening using droplet-based microfluidics.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22753519
Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor α2.
The Journal of biological chemistry Aug, 2012 | Pubmed ID: 22778273
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2012 | Pubmed ID: 22932670
NQO1 activation regulates angiotensin-converting enzyme shedding in spontaneously hypertensive rats.
Cardiovascular research Sep, 2013 | Pubmed ID: 23749777
The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.
Stem cells translational medicine Sep, 2013 | Pubmed ID: 23926209
Intranasal delivery of mesenchymal stem cells significantly extends survival of irradiated mice with experimental brain tumors.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2014 | Pubmed ID: 24002694
Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model.
Journal of neuroimmunology Jan, 2014 | Pubmed ID: 24268287
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2014 | Pubmed ID: 24691018
Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy.
Expert opinion on drug delivery Nov, 2014 | Pubmed ID: 25005767
βIII-Tubulin Regulates Breast Cancer Metastases to the Brain.
Molecular cancer therapeutics May, 2015 | Pubmed ID: 25724666
Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
Cancer research May, 2015 | Pubmed ID: 25808868
IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Cancer research Jun, 2015 | Pubmed ID: 25896327
Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2015 | Pubmed ID: 26026061
A Genetically Modified Adenoviral Vector with a Phage Display-Derived Peptide Incorporated into Fiber Fibritin Chimera Prolongs Survival in Experimental Glioma.
Human gene therapy Sep, 2015 | Pubmed ID: 26058317
Neural Stem Cells Secreting Anti-HER2 Antibody Improve Survival in a Preclinical Model of HER2 Overexpressing Breast Cancer Brain Metastases.
Stem cells (Dayton, Ohio) Oct, 2015 | Pubmed ID: 26260958
Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2016 | Pubmed ID: 26514825
Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Feb, 2016 | Pubmed ID: 26564318
A novel single-chain antibody redirects adenovirus to IL13Rα2-expressing brain tumors.
Scientific reports Dec, 2015 | Pubmed ID: 26656559
Rotating magnetic field induced oscillation of magnetic particles for in vivo mechanical destruction of malignant glioma.
Journal of controlled release : official journal of the Controlled Release Society Feb, 2016 | Pubmed ID: 26708022
Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma.
Stem cell reports Sep, 2016 | Pubmed ID: 27594591
Transgenic expression of IL15 improves antiglioma activity of IL13Ralpha2-CAR T cells but results in antigen-loss variants.
Cancer immunology research May, 2017 | Pubmed ID: 28550091