Accedi

Liakot A Khan

Mucosal Immunology and Biology Research Center,
Developmental Biology and Genetics Core,
Massachusetts General Hospital,
Massachusetts General Hospital for Children,
Mucosal Immunology and Biology Research Center, Developmental Biology and Genetics Core, Massachusetts General Hospital,
Mucosal Immunology and Biology Research Center, Developmental Biology and Genetics Core, Massachusetts General Hospital for Children

Harvard Medical School

BIOGRAPHY

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PUBLICATIONS

Modulation of EGF receptor-mediated vulva development by the heterotrimeric G-protein Galphaq and excitable cells in C. elegans.

Development (Cambridge, England) Oct, 2003 | Pubmed ID: 12925583

Molecular and functional analysis of Caenorhabditis elegans CHIP, a homologue of Mammalian CHIP.

FEBS letters May, 2004 | Pubmed ID: 15135044

Expanded polyglutamines impair synaptic transmission and ubiquitin-proteasome system in Caenorhabditis elegans.

Journal of neurochemistry Jul, 2006 | Pubmed ID: 16805848

Genetic impairment of autophagy intensifies expanded polyglutamine toxicity in Caenorhabditis elegans.

Biochemical and biophysical research communications Apr, 2008 | Pubmed ID: 18261464

Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis.

Nature cell biology Sep, 2011 | Pubmed ID: 21926990

Clathrin and AP-1 regulate apical polarity and lumen formation during C. elegans tubulogenesis.

Development (Cambridge, England) Jun, 2012 | Pubmed ID: 22535410

Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux.

Nature cell biology Feb, 2013 | Pubmed ID: 23334498

Vesicular sorting controls the polarity of expanding membranes in the C. elegans intestine.

Worm Jan, 2013 | Pubmed ID: 24058862

RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic acid-based metabolites such as lipids.

Nature protocols May, 2015 | Pubmed ID: 25837419

Corrigendum: RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic acid-based metabolites such as lipids.

Nature protocols Jun, 2015 | Pubmed ID: 26020617

Facilitation of Endosomal Recycling by an IRG Protein Homolog Maintains Apical Tubule Structure in Caenorhabditis elegans.

Genetics Aug, 2016 | Pubmed ID: 27334269

INSTITUTIONS

Harvard Medical School

JOVE ARTICLES

The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging

Nan Zhang^1,2,

Liakot A Khan¹,

Edward Membreno¹,

Gholamali Jafari¹,

Siyang Yan¹,

Hongjie Zhang^1,3,

Verena Gobel¹

¹Mucosal Immunology and Biology Research Center, Developmental Biology and Genetics Core, Massachusetts General Hospital, Harvard Medical School,

²College of Life Sciences, Jilin University,

³Faculty of Health Sciences, University of Macau

Developmental Biology

The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging

Nan Zhang^1,2,

Edward Membreno¹,

Susan Raj¹,

Hongjie Zhang^1,3,

Liakot A Khan¹,

Verena Gobel¹

¹Mucosal Immunology and Biology Research Center, Developmental Biology and Genetics Core, Massachusetts General Hospital for Children, Harvard Medical School,

²College of Life Sciences, Jilin University,

³Faculty of Health Sciences, University of Macau

Developmental Biology

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