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Department of Hematology
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High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2005 | Pubmed ID: 16166428
Positive selection for CD90 as a purging option in acute myeloid leukemia stem cell transplants.
Cytometry. Part B, Clinical cytometry Jan, 2008 | Pubmed ID: 18061946
Correlation of minimal residual disease cell frequency with molecular genotype in patients with acute myeloid leukemia.
Haematologica Jan, 2009 | Pubmed ID: 19042917
Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia.
Stem cells (Dayton, Ohio) Dec, 2008 | Pubmed ID: 19096043
Interleukin-2 receptor alpha-chain (CD25) expression on leukaemic blasts is predictive for outcome and level of residual disease in AML.
European journal of cancer (Oxford, England : 1990) Jun, 2009 | Pubmed ID: 19321337
Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cells.
PloS one , 2013 | Pubmed ID: 24244383
High class II-associated invariant chain peptide expression on residual leukemic cells is associated with increased relapse risk in acute myeloid leukemia.
Leukemia research Jun, 2014 | Pubmed ID: 24731748
A Phase 2 study of bortezomib combined with either idarubicin/cytarabine or cytarabine/etoposide in children with relapsed, refractory or secondary acute myeloid leukemia: a report from the Children's Oncology Group.
Pediatric blood & cancer Oct, 2014 | Pubmed ID: 24976003
Leukemic stem cell frequency: a strong biomarker for clinical outcome in acute myeloid leukemia.
PloS one , 2014 | Pubmed ID: 25244440
VU University medical center
Jacqueline Cloos*,1,2,
Jeffrey R. Harris*,3,
Jeroen J.W.M. Janssen1,
Angele Kelder1,
F. Huang3,
Gerrit Sijm1,
Maike Vonk1,
Alexander N. Snel1,
Jennifer R. Scheick1,
Willemijn J. Scholten1,
Jannemieke Carbaat-Ham1,
Dennis Veldhuizen1,
Diana Hanekamp1,
Yvonne J.M. Oussoren-Brockhoff1,
Gertjan J.L. Kaspers2,4,
Gerrit J. Schuurhuis1,
A. Kate Sasser3,
Gert Ossenkoppele1
1Department of Hematology, VU University Medical Center,
2Pediatric Oncology/Hematology, VU University Medical Center,
3, Janssen Research & Development, LLC,
4, Princess Máxima Center for Pediatric Oncology
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