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Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection.
Infection and immunity Dec, 1999 | Pubmed ID: 10569777
The leptospiral major outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection.
Infection and immunity Apr, 2000 | Pubmed ID: 10722630
Leptospiral proteins recognized during the humoral immune response to leptospirosis in humans.
Infection and immunity Aug, 2001 | Pubmed ID: 11447174
Evaluation of recombinant Leptospira antigen-based enzyme-linked immunosorbent assays for the serodiagnosis of leptospirosis.
Journal of clinical microbiology Sep, 2001 | Pubmed ID: 11526167
Novel 45-kilodalton leptospiral protein that is processed to a 31-kilodalton growth-phase-regulated peripheral membrane protein.
Infection and immunity Jan, 2002 | Pubmed ID: 11748198
Characterization of the leptospiral outer membrane and description of three novel leptospiral membrane proteins.
Infection and immunity Sep, 2002 | Pubmed ID: 12183539
Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily.
Molecular microbiology Aug, 2003 | Pubmed ID: 12890019
Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA.
Infection and immunity Jan, 2005 | Pubmed ID: 15618142
Surfaceome of Leptospira spp.
Infection and immunity Aug, 2005 | Pubmed ID: 16040999
LruA and LruB, novel lipoproteins of pathogenic Leptospira interrogans associated with equine recurrent uveitis.
Infection and immunity Nov, 2005 | Pubmed ID: 16239521
Lipoprotein computational prediction in spirochaetal genomes.
Microbiology (Reading, England) Jan, 2006 | Pubmed ID: 16385121
LipL46 is a novel surface-exposed lipoprotein expressed during leptospiral dissemination in the mammalian host.
Microbiology (Reading, England) Dec, 2006 | Pubmed ID: 17159228
Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen.
Infection and immunity May, 2007 | Pubmed ID: 17296754
Leptospira immunoglobulin-like proteins as a serodiagnostic marker for acute leptospirosis.
Journal of clinical microbiology May, 2007 | Pubmed ID: 17360842
Response of Leptospira interrogans to physiologic osmolarity: relevance in signaling the environment-to-host transition.
Infection and immunity Jun, 2007 | Pubmed ID: 17371863
Osmotic regulation of expression of two extracellular matrix-binding proteins and a haemolysin of Leptospira interrogans: differential effects on LigA and Sph2 extracellular release.
Microbiology (Reading, England) Oct, 2007 | Pubmed ID: 17906138
Leptospira: a spirochaete with a hybrid outer membrane.
Molecular microbiology Jun, 2010 | Pubmed ID: 20598085
The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans.
PloS one , 2011 | Pubmed ID: 21347378
A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.
PLoS neglected tropical diseases Dec, 2011 | Pubmed ID: 22180800
Antibodies to a novel leptospiral protein, LruC, in the eye fluids and sera of horses with Leptospira-associated uveitis.
Clinical and vaccine immunology : CVI Jan, 2012 | Pubmed ID: 22237897
Positive regulation of Leptospira interrogans kdp expression by KdpE as Demonstrated with a novel β-galactosidase reporter in Leptospira biflexa.
Applied and environmental microbiology Aug, 2012 | Pubmed ID: 22685146
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins.
Journal of bacteriology Nov, 2012 | Pubmed ID: 22961849
Role for cis-acting RNA sequences in the temperature-dependent expression of the multiadhesive lig proteins in Leptospira interrogans.
Journal of bacteriology Nov, 2013 | Pubmed ID: 24013626
Kinetics of Leptospira interrogans infection in hamsters after intradermal and subcutaneous challenge.
PLoS neglected tropical diseases Nov, 2014 | Pubmed ID: 25411782
Role of sph2 Gene Regulation in Hemolytic and Sphingomyelinase Activities Produced by Leptospira interrogans.
PLoS neglected tropical diseases , 2015 | Pubmed ID: 26274394
High-Throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants during Acute Infection.
PLoS neglected tropical diseases Nov, 2016 | Pubmed ID: 27824878
Immunoprotective properties of recombinant LigA and LigB in a hamster model of acute leptospirosis.
PloS one , 2017 | Pubmed ID: 28704385
1, Veterans Affairs Greater Los Angeles Healthcare System,
2Departments of Medicine, David Geffen School of Medicine at University of California Los Angeles,
3Departments of Urology, David Geffen School of Medicine at University of California Los Angeles,
4Departments of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles