Key Laboratory of Cancer Proteomics of Chinese Ministry of Health,
Xiangya Hospital,
Hunan Engineering Laboratory for Structural Biology and Drug Design,
State Local Joint Engineering Laboratory for Anticancer Drugs,
The State Key Laboratory of Medical Genetics,
National Clinical Research Center for Geriatric Disorders,
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital,
Hunan Engineering Laboratory for Structural Biology and Drug Design, Xiangya Hospital,
State Local Joint Engineering Laboratory for Anticancer Drugs, Xiangya Hospital,
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital
Xianquan Zhan received his M.D. and Ph.D. training in preventive medicine at West China University of Medical Sciences during 1989-1999. He received his post-doctoral training in oncology and cancer proteomics at Central South University and University of Tennessee Health Science Center (UTHSC). He worked at UTHSC and Cleveland Clinic in USA during 2001-2012, and achieved the rank of Associate Professor at UTHSC. In 2012, he moved to Central South University Xiangya Hospital as a Professor, and Advisors of MS/PhD graduate students and postdoctoral fellows. He is also the Fellow of Royal Society of Medicine, Fellow of EPMA, European EPMA National Representative, AAAS member, Editor-In-Chief of IJCDT, Execute Editor-in-Chief of Med One, Associate Editors of EPMA Journal and BMC Medical Genomics, and Guest Editors of Frontiers in Endocrinology (IF = 3.65) and Mass Spectrometry Reviews (IF = 9.068). He has published 130 articles, 16 book chapters, 3 books, and 2 US patents in the field of clinical proteomics and biomarkers. His research interests focus on the development and use of multi-omics (genomics, transcriptomics, proteomics, metabolomics, and radiomics) and systems biology to study cancer mechanisms, and discover effective biomarker pattern for predictive, preventive, and personalized medicine (PPPM) or precission medicine (PM) in cancer, and also focus on cancer proteoforms and post-translational modifications (PTMs).
Comparative proteomics analysis of human lung squamous carcinoma.
Biochemical and biophysical research communications Sep, 2003 | Pubmed ID: 12943690
Proteomic comparison of two-dimensional gel electrophoresis profiles from human lung squamous carcinoma and normal bronchial epithelial tissues.
Genomics, proteomics & bioinformatics Feb, 2003 | Pubmed ID: 15626334
Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis.
Brain research Feb, 2012 | Pubmed ID: 22284620
Proteomic and bioinformatics analyses of mouse liver microsomes.
International journal of proteomics , 2012 | Pubmed ID: 22500222
Mitochondrial proteomics of nasopharyngeal carcinoma metastasis.
BMC medical genomics Dec, 2012 | Pubmed ID: 23217164
Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer.
The EPMA journal Jan, 2013 | Pubmed ID: 23339750
[Effect of DJ-1 siRNA on biological behavior of human lung squamous carcinoma SK-MES-1 cells].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences Jan, 2013 | Pubmed ID: 23406859
Pituitary adenoma nitroproteomics: current status and perspectives.
Oxidative medicine and cellular longevity , 2013 | Pubmed ID: 23533694
Identification of stromal differentially expressed proteins in the colon carcinoma by quantitative proteomics.
Electrophoresis Jun, 2013 | Pubmed ID: 23737015
Mapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell line.
BMC cancer Nov, 2013 | Pubmed ID: 24209905
Mass spectrometry analysis of nitrotyrosine-containing proteins.
Mass spectrometry reviews Jul-Aug, 2015 | Pubmed ID: 24318073
VE-statin/Egfl7 expression in malignant glioma and its relevant molecular network.
International journal of clinical and experimental pathology , 2014 | Pubmed ID: 24696719
VE-statin/Egfl7 siRNA inhibits angiogenesis in malignant glioma in vitro.
International journal of clinical and experimental pathology , 2014 | Pubmed ID: 24696724
Identification of the proteomic variations of invasive relative to non-invasive non-functional pituitary adenomas.
Electrophoresis Aug, 2014 | Pubmed ID: 24729304
Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas.
BMC medical genomics Dec, 2014 | Pubmed ID: 25539738
Proteomic and functional profiles of a follicle-stimulating hormone positive human nonfunctional pituitary adenoma.
Electrophoresis Jun, 2015 | Pubmed ID: 25809007
EPMA position paper in cancer: current overview and future perspectives.
The EPMA journal , 2015 | Pubmed ID: 25908947
Identification of Glioblastoma Phosphotyrosine-Containing Proteins with Two-Dimensional Western Blotting and Tandem Mass Spectrometry.
BioMed research international , 2015 | Pubmed ID: 26090378
Nitroproteins in Human Astrocytomas Discovered by Gel Electrophoresis and Tandem Mass Spectrometry.
Journal of the American Society for Mass Spectrometry Dec, 2015 | Pubmed ID: 26450359
Exploration of Molecular Network Variations in Different Subtypes of Human Non-functional Pituitary Adenomas.
Frontiers in endocrinology , 2016 | Pubmed ID: 26903949
Human Pituitary Adenoma Proteomics: New Progresses and Perspectives.
Frontiers in endocrinology , 2016 | Pubmed ID: 27303365
Editorial: Systems Biological Aspects of Pituitary Tumors.
Frontiers in endocrinology , 2016 | Pubmed ID: 27445988
Pattern recognition for predictive, preventive, and personalized medicine in cancer.
The EPMA journal Mar, 2017 | Pubmed ID: 28620443
Exploration of variations in proteome and metabolome for predictive diagnostics and personalized treatment algorithms: Innovative approach and examples for potential clinical application.
Journal of proteomics Aug, 2017 | Pubmed ID: 28851587
Proteomic Identification of an Upregulated Isoform of Annexin A3 in the Spinal Cords of Rats in a Neuropathic Pain Model.
Frontiers in neuroscience , 2017 | Pubmed ID: 28928629
How many proteins can be identified in a 2DE gel spot within an analysis of a complex human cancer tissue proteome?
Electrophoresis Dec, 2017 | Pubmed ID: 29205401
Protein tyrosine nitration in lung cancer: current research status and future perspectives.
Current medicinal chemistry Feb, 2018 | Pubmed ID: 29473494
The crucial role of multiomic approach in cancer research and clinically relevant outcomes.
The EPMA journal Mar, 2018 | Pubmed ID: 29515689
The lncRNA SNHG3 regulates energy metabolism of ovarian cancer by an analysis of mitochondrial proteomes.
Gynecologic oncology 08, 2018 | Pubmed ID: 29921511
Quantitative analysis of the mitochondrial proteome in human ovarian carcinomas.
Endocrine-related cancer 10, 2018 | Pubmed ID: 29997262
The differentially mitochondrial proteomic dataset in human ovarian cancer relative to control tissues.
Data in brief Oct, 2018 | Pubmed ID: 30186894
Prolactin Variants in Human Pituitaries and Pituitary Adenomas Identified With Two-Dimensional Gel Electrophoresis and Mass Spectrometry.
Frontiers in endocrinology , 2018 | Pubmed ID: 30210449
Quantitative Analysis of Ubiquitinated Proteins in Human Pituitary and Pituitary Adenoma Tissues.
Frontiers in endocrinology , 2019 | Pubmed ID: 31191455
The MAPK Pathway-Based Drug Therapeutic Targets in Pituitary Adenomas.
Frontiers in endocrinology , 2019 | Pubmed ID: 31231308
Signaling pathway network alterations in human ovarian cancers identified with quantitative mitochondrial proteomics.
The EPMA journal Jun, 2019 | Pubmed ID: 31258820
Quantitative analysis of the human ovarian carcinoma mitochondrial phosphoproteome.
Aging Aug, 2019 | Pubmed ID: 31442208
Identification of clinical trait-related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer.
The EPMA journal Sep, 2019 | Pubmed ID: 31462944
Mitochondrial Dysfunction Pathway Networks and Mitochondrial Dynamics in the Pathogenesis of Pituitary Adenomas.
Frontiers in endocrinology , 2019 | Pubmed ID: 31649621
Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level.
Proteomes Oct, 2019 | Pubmed ID: 31671630
1Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University,
2Hunan Engineering Laboratory for Structural Biology and Drug Design, Xiangya Hospital, Central South University,
3State Local Joint Engineering Laboratory for Anticancer Drugs, Xiangya Hospital, Central South University,
4The State Key Laboratory of Medical Genetics, Central South University
1Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University,
2Hunan Engineering Laboratory for Structural Biology and Drug Design, Xiangya Hospital, Central South University,
3State Local Joint Engineering Laboratory for Anticancer Drugs, Xiangya Hospital, Central South University,
4National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University,
5Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University