Massimo Gadina

Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer.

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection.

Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights.

New interleukins: are there any more?

Cytokines and their role in lymphoid development, differentiation and homeostasis.

Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.

Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory.

Ubiquitination for activation: new directions in the NF-kappaB roadmap.

CXCL12 signaling is independent of Jak2 and Jak3.

G(i)-protein-dependent inhibition of IL-12 production is mediated by activation of the phosphatidylinositol 3-kinase-protein 3 kinase B/Akt pathway and JNK.

Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.

Cytohesin binder and regulator (cybr) is not essential for T- and dendritic-cell activation and differentiation.

The newest interleukins: recent additions to the ever-growing cytokine family.

Immunodeficiency is a tough nut to CRAC: the importance of calcium flux in T cell activation.

Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase.

IL-33: a sheep in wolf's clothing?

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist.

Immune modulation: Turncoat regulatory T cells.

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).

Cytokine signaling: birth of a pathway.

A novel mutation of IL1RN in the deficiency of interleukin-1 receptor antagonist syndrome: description of two unrelated cases from Brazil.