Ellen A. Nollen

Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.

C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging.

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip.

Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms.

A FRET sensor for non-invasive imaging of amyloid formation in vivo.

SERF protein is a direct modifier of amyloid fiber assembly.

Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.

Tryptophan metabolism: entering the field of aging and age-related pathologies.

Analyzing modifiers of protein aggregation in C. elegans by native agarose gel electrophoresis.

Genetic screens in Caenorhabditis elegans models for neurodegenerative diseases.

Regulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genes.

An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.

Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease.

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.

Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.

Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.

MOAG-4 promotes the aggregation of α-synuclein by competing with self-protective electrostatic interactions.

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.

Filter Retardation Assay for Detecting and Quantifying Polyglutamine Aggregates Using Lysates.

Nuclear/Cytoplasmic Fractionation of Proteins from .