Department of Chemistry
Dr. Liangliang Sun is an Assistant Professor in the Department of Chemistry at Michigan State University (East Lansing, Michigan, USA). He received his Ph.D. in Analytical Chemistry from Dalian Institute of Chemical Physics, Chinese Academy of Sciences (Dalian, China) in 2011. Then he worked with Prof. Norman Dovichi as a postdoctoral fellow and later as a research assistant professor from 2011 to 2016 at the University of Notre Dame (Notre Dame, Indiana, USA). He joined Michigan State University as an Assistant Professor in 2016. He has 12-years’ experiences on proteomics and has published 84 peer-reviewed papers with over 1700 citations.
Dr. Sun’s research group at MSU aims to develop novel analytical methodologies based on capillary zone electrophoresis-tandem mass spectrometry (CZE-MS/MS) for comprehensive and highly sensitive bottom-up and top-down proteomics. His research group applies those methodologies for quantitative proteomics of zebrafish embryos and blastomeres during early embryogenesis to achieve the dynamics of gene expression and protein post-translational modifications (PTMs) during early embryogenesis at high time resolution and single-cell resolution.
Simplified capillary isoelectric focusing with chemical mobilization for intact protein analysis.
Journal of separation science Feb, 2017 | Pubmed ID: 27935257
Evaluation of a commercial electro-kinetically pumped sheath-flow nanospray interface coupled to an automated capillary zone electrophoresis system.
Analytical and bioanalytical chemistry Mar, 2017 | Pubmed ID: 27981343
Predicting Electrophoretic Mobility of Tryptic Peptides for High-Throughput CZE-MS Analysis.
Analytical chemistry Feb, 2017 | Pubmed ID: 28208305
Capillary zone electrophoresis-mass spectrometry with microliter-scale loading capacity, 140 min separation window and high peak capacity for bottom-up proteomics.
The Analyst Jun, 2017 | Pubmed ID: 28513658
Single-Shot Top-Down Proteomics with Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry for Identification of Nearly 600 Escherichia coli Proteoforms.
Analytical chemistry Nov, 2017 | Pubmed ID: 29064224
Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development.
Scientific reports Nov, 2017 | Pubmed ID: 29142207
Site-Specific Glycan Heterogeneity Characterization by Hydrophilic Interaction Liquid Chromatography Solid-Phase Extraction, Reversed-Phase Liquid Chromatography Fractionation, and Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry.
Analytical chemistry Jan, 2018 | Pubmed ID: 29231704
Quantitative Proteomics After Spinal Cord Injury (SCI) in a Regenerative and a Nonregenerative Stage in the Frog .
Molecular & cellular proteomics : MCP Apr, 2018 | Pubmed ID: 29358338
Strong cation exchange-reversed phase liquid chromatography-capillary zone electrophoresis-tandem mass spectrometry platform with high peak capacity for deep bottom-up proteomics.
Analytica chimica acta Jul, 2018 | Pubmed ID: 29475469
Systematic Evaluation of Immobilized Trypsin-Based Fast Protein Digestion for Deep and High-Throughput Bottom-Up Proteomics.
Proteomics May, 2018 | Pubmed ID: 29577644
Deep Top-Down Proteomics Using Capillary Zone Electrophoresis-Tandem Mass Spectrometry: Identification of 5700 Proteoforms from the Escherichia coli Proteome.
Analytical chemistry May, 2018 | Pubmed ID: 29620868
Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan.
Scientific reports May, 2018 | Pubmed ID: 29844480
Native Proteomics in Discovery Mode Using Size-Exclusion Chromatography-Capillary Zone Electrophoresis-Tandem Mass Spectrometry.
Analytical chemistry Sep, 2018 | Pubmed ID: 30085653
Microscale Reversed-Phase Liquid Chromatography/Capillary Zone Electrophoresis-Tandem Mass Spectrometry for Deep and Highly Sensitive Bottom-Up Proteomics: Identification of 7500 Proteins with Five Micrograms of an MCF7 Proteome Digest.
Analytical chemistry Sep, 2018 | Pubmed ID: 30102516